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Gene: Rap1a (RAP1A, member of RAS oncogene family) Rattus norvegicus
Symbol: Rap1a
Name: RAP1A, member of RAS oncogene family
Description: Exhibits GTP binding activity and Rap guanyl-nucleotide exchange factor activity. Involved in several processes, including cellular response to cAMP; positive regulation of protein phosphorylation; and positive regulation of transport. Localizes to the cytoplasmic vesicle and perinuclear region of cytoplasm. Orthologous to human RAP1A (RAP1A, member of RAS oncogene family); PARTICIPATES IN adenosine signaling pathway; E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; 8-bromo-3',5'-cyclic AMP.
Type: protein-coding
Also known as: MGC93785; MGC94873; rap 1A; RAP-1A; RAS-related protein 1a; ras-related protein Krev-1; Ras-related protein RAP-1A
Homo sapiens (human) : RAP1A (RAP1A, member of RAS oncogene family)  HGNC  Alliance
Mus musculus (house mouse) : Rap1a (RAS-related protein 1a)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rap1a (RAP1A, member of RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAP1A (RAP1A, member of RAS oncogene family)
Canis lupus familiaris (dog) : RAP1A (RAP1A, member of RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rap1a (RAP1A, member of RAS oncogene family)
Sus scrofa (pig) : RAP1A (RAP1A, member of RAS oncogene family)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02208,193,950 - 208,215,186 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02227,614,901 - 227,691,823 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42200,980,324 - 201,001,561 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12200,943,077 - 201,020,962 (-)NCBI
Celera2185,670,857 - 185,692,256 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Rap1a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1359694
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.