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Gene: Fhem1 (fumarate hydratase; TALEN induced mutant 1) Rattus norvegicus
Symbol: Fhem1
Name: fumarate hydratase; TALEN induced mutant 1
Description: A pair of TALENs targeting exon 1 of the Fh gene was injected into SD embryos to create Fh knock out mutants. The resulting mutation was an 11-bp deletion (acacctttggt) on exon 1 that caused premature stop of FH protein.
ASSOCIATED WITH abnormal kidney morphology; abnormal lymphocyte morphology; decreased blood uric acid level
Type: allele  of Fh  
Is Marker For: Strains:   SD-Fhem1+/-  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position: No map positions available.

References - curated


Related Rat Strains



Nucleotide Sequences

Additional Information

Nomenclature History
More on Fhem1
Alliance Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 13792797
Created: 2018-09-28
Species: Rattus norvegicus
Last Modified: 2018-09-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.