Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MIR374B (microRNA mir-374b) Sus scrofa
Analyze
Symbol: MIR374B
Name: microRNA mir-374b
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: microRNA 374b; ssc-mir-374b
Orthologs:
Homo sapiens (human) : MIR374B (microRNA 374b)  HGNC  Alliance
Mus musculus (house mouse) : Mir374c (microRNA 374c)  MGI
Rattus norvegicus (Norway rat) : Mir374b (microRNA 374b)  Alliance
Canis lupus familiaris (dog) : MIR374B (microRNA mir-374b)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X59,551,146 - 59,551,225 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X67,425,186 - 67,425,265 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig CytomapX NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
References - uncurated

Genomics

Comparative Map Data

Sequence

Nucleotide Sequences

Additional Information

External Database Links
Nomenclature History
 
More on MIR374B
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 13853444
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2019-09-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.