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Gene: ALOX5AP (arachidonate 5-lipoxygenase activating protein) Sus scrofa
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Symbol: ALOX5AP
Name: arachidonate 5-lipoxygenase activating protein
Description: ENCODES a protein that exhibits arachidonic acid binding (ortholog); INVOLVED IN cellular oxidant detoxification (inferred); leukotriene production involved in inflammatory response (inferred); positive regulation of catalytic activity (inferred); PARTICIPATES IN leukotriene metabolic pathway; lipoxygenase mediated pathway of arachidonic acid metabolism; ASSOCIATED WITH arteriosclerosis (ortholog); atherosclerosis (ortholog); brain infarction (ortholog); FOUND IN nuclear envelope (ortholog); nuclear membrane (ortholog); INTERACTS WITH 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid; aristolochic acid
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5-lipoxygenase-activating protein; arachidonate 5-lipoxygenase-activating protein; FLAP; MK-886-binding protein
Orthologs:
Homo sapiens (human) : ALOX5AP (arachidonate 5-lipoxygenase activating protein)  HGNC  Alliance
Mus musculus (house mouse) : Alox5ap (arachidonate 5-lipoxygenase activating protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Alox5ap (arachidonate 5-lipoxygenase activating protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alox5ap (arachidonate 5-lipoxygenase activating protein)
Pan paniscus (bonobo/pygmy chimpanzee) : ALOX5AP (arachidonate 5-lipoxygenase activating protein)
Canis lupus familiaris (dog) : ALOX5AP (arachidonate 5-lipoxygenase activating protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alox5ap (arachidonate 5-lipoxygenase activating protein)
Chlorocebus sabaeus (African green monkey) : ALOX5AP (arachidonate 5-lipoxygenase activating protein)
Heterocephalus glaber (naked mole-rat) : Alox5ap (arachidonate 5-lipoxygenase activating protein)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl117,411,644 - 7,438,108 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1117,371,328 - 7,438,111 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2117,222,771 - 7,287,566 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on ALOX5AP
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 13872518
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-02-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.