Gene: ITGB2 (integrin subunit beta 2) Sus scrofa |
|
 Analyze |
Symbol: |
ITGB2 |
Name: |
integrin subunit beta 2 |
Description: |
ENCODES a protein that exhibits cell adhesion molecule binding (inferred); heat shock protein binding (inferred); ICAM-3 receptor activity (inferred); INVOLVED IN integrin-mediated signaling pathway; positive regulation of phagocytosis; cellular response to low-density lipoprotein particle stimulus (ortholog); PARTICIPATES IN Entamoebiasis pathway; hypoxia inducible factor pathway; integrin mediated signaling pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); acute promyelocytic leukemia (ortholog); allergic hypersensitivity disease (ortholog); FOUND IN membrane (ortholog); INTERACTS WITH bis(2-chloroethyl) sulfide; dibromine; Estradiol 17beta-cyclopentylpropionate |
Type: |
protein-coding
|
RefSeq Status: |
PROVISIONAL |
Also known as: |
CD18; CD18 leukocyte adhesion molecule; cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement receptor C3 subunit beta; integrin beta-2 |
Orthologs: |
|
Latest Assembly: |
Sscrofa11.1 - Pig Sscrofa11.1 Assembly |
Position: |
|
JBrowse: |
View Region in Genome Browser (JBrowse)
|
Model |
|
 Disease Annotations
CRRD Manual Annotations
Acute Lung Injury | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:1374449, REF_RGD_ID:6482199 | Cerebral Hemorrhage | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:18615643, REF_RGD_ID:6482197 | Chronic Periodontitis | | ISS | RGD:12691416 | 9068941 | mRNA:increased expression:gingival tissues | RGD | PMID:21382035, REF_RGD_ID:6480655 | colitis | | ISS | RGD:12691416 | 9068941 | associated with Spirochaetales infections | RGD | PMID:11031123, REF_RGD_ID:6482227 | coronary restenosis | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:11703955, REF_RGD_ID:1581185 | Enterocolitis | | ISS | RGD:12691416 | 9068941 | associated with Hirschsprung Disease, DNA:polymorphisms:multiple | RGD | PMID:18675632, REF_RGD_ID:6482226 | Eosinophilic Myocarditis | treatment | ISS | RGD:12691416 | 9068941 | | RGD | PMID:9822282, REF_RGD_ID:13702914 | Experimental Arthritis | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:8881759, REF_RGD_ID:6482229 | glomerulonephritis | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:19752320, REF_RGD_ID:6907051 | glomerulonephritis | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:15277234, REF_RGD_ID:6907066 | Kidney Neoplasms | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:11907109, REF_RGD_ID:6907072 | Kidney Reperfusion Injury | | ISS | RGD:12691416 | 9068941 | Associated with renal transplant patients | RGD | PMID:20504838, REF_RGD_ID:6907049 | Kidney Reperfusion Injury | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:11007822, REF_RGD_ID:6907073 | leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | DNA:mutation:exon:p.R188X(human) | RGD | PMID:21103413, REF_RGD_ID:6482223 | leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | DNA:deletion, nonsense mutations:exons:1622_1657del, 2200G>T (human) | RGD | PMID:14512306, REF_RGD_ID:6482225 | leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | DNA:point_mutations:CDS:compound heterozygote, amino acid arg593cys and lys196thr | RGD | PMID:1968911, REF_RGD_ID:1600220 | leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | DNA:mutations:multiple | RGD | PMID:20549317, REF_RGD_ID:6482224 | leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | DNA:mutations:cds:p.D231H, G284S (human) | RGD | PMID:10886250, REF_RGD_ID:6482222 | myocarditis | | ISS | RGD:12691416 | 9068941 | protein:increased expression:serum | RGD | PMID:9556870, REF_RGD_ID:13702915 | nephritis | treatment | ISS | RGD:12691416 | 9068941 | | RGD | PMID:8773354, REF_RGD_ID:8547716 | pancreatitis | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:22490516, REF_RGD_ID:6482196 | Plaque, Atherosclerotic | | ISS | RGD:12691416 | 9068941 | mRNA:increased expression:artery | RGD | PMID:26188538, REF_RGD_ID:11085957 | pneumonia | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:10030843, REF_RGD_ID:6482228 | psoriasis | | ISS | RGD:12691416 | 9068941 | | RGD | PMID:19812597, REF_RGD_ID:6482221 | Vogt-Koyanagi-Harada disease | | ISS | RGD:12691416 | 9068941 | protein:decreased expression:T cell | RGD | PMID:21297967, REF_RGD_ID:6482200 | |
Imported Annotations - ClinVar
|
autistic disorder | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Autistic disorder of childhood onset | ClinVar | PMID:21681106, PMID:30208311 |
autoimmune polyendocrine syndrome type 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Polyglandular autoimmune syndrome, type 1 | ClinVar | PMID:28492532 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:1590804 more ... |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:1346613 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:24033266 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:25741868, PMID:9884339 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:28492532 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:1590804 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:1346613, PMID:6237120 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:10712675 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:9884339 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:24033266, PMID:28492532 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:1694220 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:12488604 more ... |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:12488604 more ... |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:1347532 more ... |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:1968911 |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | |
leukocyte adhesion deficiency | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency | ClinVar | PMID:1346613 more ... |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:22134107 more ... |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:1346613 more ... |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:20549317 |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:28492532 |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:12488604 more ... |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:1590804 more ... |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:24033266 |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:18675632, PMID:28492532 |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:25741868, PMID:9884339 |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:25741868, PMID:28492532 |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:25741868 |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:12488604 more ... |
leukocyte adhesion deficiency 1 | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Leukocyte adhesion deficiency type 1 | ClinVar | PMID:24033266, PMID:28492532 |
Neurodevelopmental Disorders | | ISS | RGD:12691416 | 9068941 | ClinVar Annotator: match by term: Neurodevelopmental disorder | ClinVar | PMID:25741868 |