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Gene: CFLAR (CASP8 and FADD like apoptosis regulator) Sus scrofa
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Symbol: CFLAR
Name: CASP8 and FADD like apoptosis regulator
Description: ENCODES a protein that exhibits cysteine-type endopeptidase activity (inferred); peptidase activator activity (inferred); protease binding (inferred); INVOLVED IN apoptotic signaling pathway (inferred); negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (inferred); negative regulation of myoblast fusion (inferred); PARTICIPATES IN apoptotic cell death pathway; Chagas disease pathway; FasL mediated signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Carotid Artery Injuries (ortholog); congestive heart failure (ortholog); FOUND IN death-inducing signaling complex (inferred); ripoptosome (inferred); INTERACTS WITH lipopolysaccharide
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-FLIP; CASP8 and FADD-like apoptosis regulator; cellular FLICE-like inhibitory protein; FLIP
Orthologs:
Homo sapiens (human) : CFLAR (CASP8 and FADD like apoptosis regulator)  HGNC  Alliance
Mus musculus (house mouse) : Cflar (CASP8 and FADD-like apoptosis regulator)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cflar (CASP8 and FADD-like apoptosis regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cflar (CASP8 and FADD like apoptosis regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : CFLAR (CASP8 and FADD like apoptosis regulator)
Canis lupus familiaris (dog) : CFLAR (CASP8 and FADD like apoptosis regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cflar (CASP8 and FADD like apoptosis regulator)
Chlorocebus sabaeus (African green monkey) : CFLAR (CASP8 and FADD like apoptosis regulator)
Heterocephalus glaber (naked mole-rat) : Cflar (CASP8 and FADD like apoptosis regulator)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15104,781,615 - 104,844,921 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115104,780,744 - 104,835,631 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215116,105,245 - 116,184,924 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
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Additional Information

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More on CFLAR
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 13880069
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.