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Gene: ATF4 (activating transcription factor 4) Sus scrofa
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Symbol: ATF4
Name: activating transcription factor 4
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); leucine zipper domain binding (inferred); protein kinase binding (inferred); INVOLVED IN cellular calcium ion homeostasis (inferred); cellular response to amino acid starvation (inferred); cellular response to dopamine (inferred); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; Endoplasmic Reticulum-associated degradation pathway; gonadotropin-releasing hormone signaling pathway; ASSOCIATED WITH fatty liver disease (ortholog); Hypoxia (ortholog); invasive ductal carcinoma (ortholog); FOUND IN ATF1-ATF4 transcription factor complex (inferred); ATF4-CREB1 transcription factor complex (inferred); cell (inferred); INTERACTS WITH cadmium atom; cadmium dichloride; cycloheximide
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: activating transcription factor 4 (tax-responsive enhancer element B67); cAMP response element-binding protein 2; CREB2; cyclic AMP-dependent transcription factor ATF-4
Orthologs:
Homo sapiens (human) : ATF4 (activating transcription factor 4)  HGNC  Alliance
Mus musculus (house mouse) : Atf4 (activating transcription factor 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atf4 (activating transcription factor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atf4 (activating transcription factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ATF4 (activating transcription factor 4)
Canis lupus familiaris (dog) : ATF4 (activating transcription factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atf4 (activating transcription factor 4)
Chlorocebus sabaeus (African green monkey) : ATF4 (activating transcription factor 4)
Heterocephalus glaber (naked mole-rat) : Atf4 (activating transcription factor 4)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl58,738,880 - 8,745,225 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.158,742,964 - 8,745,752 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,042,584 - 6,044,651 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on ATF4
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 13884038
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.