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Gene: LEP (leptin) Sus scrofa
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Symbol: LEP
Name: leptin
Description: ENCODES a protein that exhibits DNA binding (ortholog); growth factor activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN bone mineralization involved in bone maturation (ortholog); cardiac muscle hypertrophy (ortholog); cellular response to L-ascorbic acid (ortholog); PARTICIPATES IN altered energy homeostasis pathway; altered leptin system pathway; energy homeostasis pathway; ASSOCIATED WITH acute pancreatitis (ortholog); adult respiratory distress syndrome (ortholog); alcohol dependence (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 17beta-estradiol; okadaic acid; progesterone
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: OB; obese; obesity factor; OBS
Orthologs:
Homo sapiens (human) : LEP (leptin)  HGNC  Alliance
Mus musculus (house mouse) : Lep (leptin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lep (leptin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lep (leptin)
Pan paniscus (bonobo/pygmy chimpanzee) : LEP (leptin)
Canis lupus familiaris (dog) : LEP (leptin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lep (leptin)
Chlorocebus sabaeus (African green monkey) : LEP (leptin)
Heterocephalus glaber (naked mole-rat) : Lep (leptin)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1820,106,868 - 20,123,447 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11820,106,867 - 20,124,071 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21821,200,988 - 21,231,275 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on LEP
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 13902885
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-08-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.