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Gene: PRKN (parkin RBR E3 ubiquitin protein ligase) Sus scrofa
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Symbol: PRKN
Name: parkin RBR E3 ubiquitin protein ligase
CRRD ID: 13919026
Description: ENCODES a protein that exhibits enzyme binding (ortholog); heat shock protein binding (ortholog); kinase binding (ortholog); INVOLVED IN autophagy of mitochondrion (ortholog); brain development (ortholog); cellular protein catabolic process (ortholog); PARTICIPATES IN altered mitochondrial autophagy pathway; mitochondrial autophagy pathway; Parkinson's disease pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Animal Disease Models (ortholog); autistic disorder (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 ubiquitin-protein ligase parkin; PARK2; Parkinson disease (autosomal recessive, juvenile) 2, parkin; parkinson protein 2, E3 ubiquitin protein ligase (parkin); pdr-1
Orthologs:
Homo sapiens (human) : PRKN (parkin RBR E3 ubiquitin protein ligase)  HGNC  Alliance
Mus musculus (house mouse) : Prkn (parkin RBR E3 ubiquitin protein ligase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prkn (parkin RBR E3 ubiquitin protein ligase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkn (parkin RBR E3 ubiquitin protein ligase)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKN (parkin RBR E3 ubiquitin protein ligase)
Canis lupus familiaris (dog) : PRKN (parkin RBR E3 ubiquitin protein ligase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkn (parkin RBR E3 ubiquitin protein ligase)
Chlorocebus sabaeus (African green monkey) : PRKN (parkin RBR E3 ubiquitin protein ligase)
Heterocephalus glaber (naked mole-rat) : Prkn (parkin RBR E3 ubiquitin protein ligase)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15,465,511 - 6,730,881 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115,698,508 - 6,731,132 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.217,649,954 - 8,260,243 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.217,197,051 - 7,562,040 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on PRKN
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 13919026
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.