Gene: LPL (lipoprotein lipase) Sus scrofa
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Symbol:
LPL
Name:
lipoprotein lipase
Description:
ENCODES a protein that exhibits heparin binding (ortholog); lipoprotein lipase activity (ortholog); INVOLVED IN response to glucose (ortholog); triglyceride catabolic process (ortholog); PARTICIPATES IN Alzheimer's disease pathway; D-glycericacidemia pathway; familial lipoprotein lipase deficiency pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); Alcoholic Liver Diseases (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH resveratrol
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
LPL (lipoprotein lipase) HGNC
Ensembl, Inparanoid, NCBI, OrthoDB, Panther
Mus musculus (house mouse):
Lpl (lipoprotein lipase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):
Lpl (lipoprotein lipase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Lpl (lipoprotein lipase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
LPL (lipoprotein lipase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
LPL (lipoprotein lipase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Lpl (lipoprotein lipase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Latest Assembly:
Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
CRRD Manual Annotations
abdominal obesity-metabolic syndrome 1 treatment ISS RGD:12536618 9068941 RGD PMID:26996629 , REF_RGD_ID:13794382 Alcoholic Liver Diseases treatment ISS RGD:12536618 9068941 RGD PMID:28442378 , REF_RGD_ID:13794376 Alzheimer's disease no_association ISS RGD:12536618 9068941 DNA:SNPs: :multiple RGD PMID:27897113 , REF_RGD_ID:13793395 Alzheimer's disease no_association ISS RGD:12536618 9068941 DNA:point mutations: :p.N291S, p.S447X (human) RGD PMID:12133567 , REF_RGD_ID:13793397 Alzheimer's disease ISS RGD:12536618 9068941 DNA:SNPs: :rs268, rs328 (human) RGD PMID:16013913 , REF_RGD_ID:5685661 Alzheimer's disease ISS RGD:12536618 9068941 DNA:point mutations: :p.N291S, p.S447X (human) RGD PMID:10206232 , REF_RGD_ID:13799353 Alzheimer's disease severity ISS RGD:12536618 9068941 DNA, mRNA:SNP, decreased expression: :rs285 (human) RGD PMID:16965549 , REF_RGD_ID:13793393 Alzheimer's disease ISS RGD:12536618 9068941 DNA:polymorphism:intron RGD PMID:15331147 , REF_RGD_ID:13793396 Alzheimer's disease ISS RGD:12536618 9068941 RGD PMID:24004859 , REF_RGD_ID:13793392 Chemical and Drug Induced Liver Injury treatment ISS RGD:12536618 9068941 RGD PMID:27071702 , REF_RGD_ID:13794380 Chronic Intermittent Hypoxia treatment ISS RGD:12536618 9068941 RGD PMID:29968701 , REF_RGD_ID:13793400 coronary artery disease ISS RGD:12536618 9068941 RGD PMID:8641022 , REF_RGD_ID:1580537 Coronary Disease ISS RGD:12536618 9068941 RGD PMID:27000070 , REF_RGD_ID:13794381 Diabetes Mellitus, Experimental ISS RGD:12536618 9068941 RGD PMID:18780778 , REF_RGD_ID:2313303 Diabetes Mellitus, Experimental treatment ISS RGD:12536618 9068941 RGD PMID:27158912 , REF_RGD_ID:13794379 Diabetic Nephropathies susceptibility ISS RGD:12536618 9068941 RGD PMID:16813599 , REF_RGD_ID:2306755 end stage renal failure ISS RGD:12536618 9068941 RGD PMID:22009636 , REF_RGD_ID:6909179 familial hyperlipidemia treatment ISS RGD:12536618 9068941 RGD PMID:29931882 , REF_RGD_ID:13794383 familial hyperlipidemia ISS RGD:12536618 9068941 RGD PMID:9920508 , REF_RGD_ID:1556571 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 RGD PMID:9973300 , REF_RGD_ID:1556752 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 RGD PMID:16431216 , REF_RGD_ID:1580533 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 DNA:missense mutation:exon:p.D156G (human) RGD PMID:1907278 , REF_RGD_ID:1302536 focal segmental glomerulosclerosis ISS RGD:12536618 9068941 RGD PMID:14531811 , REF_RGD_ID:2308781 hypertension ISS RGD:12536618 9068941 RGD PMID:16132104 , REF_RGD_ID:1580535 hypertension ISS RGD:12536618 9068941 RGD PMID:15127290 , REF_RGD_ID:1578729 Hypertriglyceridemia ISS RGD:12536618 9068941 RGD PMID:11016888 , REF_RGD_ID:2313581 Hypertriglyceridemia susceptibility ISS RGD:12536618 9068941 RGD PMID:17848837 , REF_RGD_ID:2313305 Hypertriglyceridemia ISS RGD:12536618 9068941 RGD PMID:16431216 , REF_RGD_ID:1580533 Insulin Resistance ISS RGD:12536618 9068941 RGD PMID:18952837 , REF_RGD_ID:2313300 muscular disease ISS RGD:12536618 9068941 RGD PMID:7635990 , REF_RGD_ID:1302535 myocardial infarction susceptibility ISS RGD:12536618 9068941 associated with Diabetes Mellitus, Non-Insulin-Dependent, DNA:SNP: :p.D9N (rs1801177) (human) RGD PMID:18823627 , REF_RGD_ID:2313302 non-alcoholic fatty liver disease treatment ISS RGD:12536618 9068941 RGD PMID:27978932 , REF_RGD_ID:13794377 non-alcoholic fatty liver disease treatment ISS RGD:12536618 9068941 RGD PMID:30214514 , REF_RGD_ID:13793398 obesity treatment ISS RGD:12536618 9068941 RGD PMID:28514832 , REF_RGD_ID:13793401 obesity ISS RGD:12536618 9068941 RGD PMID:18952837 , REF_RGD_ID:2313300 obesity ISS RGD:12536618 9068941 mRNA:increased expression:white fat RGD PMID:17712951 , REF_RGD_ID:2313580 obesity treatment ISS RGD:12536618 9068941 RGD PMID:27160499 , REF_RGD_ID:13794378 type 2 diabetes mellitus ISS RGD:12536618 9068941 RGD PMID:8641022 , REF_RGD_ID:1580537 type 2 diabetes mellitus treatment ISS RGD:12536618 9068941 RGD PMID:29981201 , REF_RGD_ID:13793399 type 2 diabetes mellitus ISS RGD:12536618 9068941 DNA:SNP:intron:13836C>A (rs343) (human) RGD PMID:18985010 , REF_RGD_ID:2313298 type 2 diabetes mellitus ISS RGD:12536618 9068941 associated with Obesity RGD PMID:18321693 , REF_RGD_ID:2313304
Imported Annotations - ClinVar
Coronary Disease ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Coronary heart disease ClinVar PMID:10364086 more ... familial combined hyperlipidemia ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipidemia, familial combined ClinVar PMID:25741868 , PMID:8541837 familial combined hyperlipidemia ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipidemia, familial combined ClinVar PMID:10364086 more ... familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:9714430 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:2536938 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:10364086 more ... familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:15840743 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1639392 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1907278 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:7906986 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1598907 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1511985 more ... familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:2294743 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1530621 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Lipase D deficiency ClinVar PMID:1562620 more ... familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:2110364 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:8288243 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:22239554 more ... familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:20650961 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1702428 more ... familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:23246289 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:2121025 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1937490 , PMID:2121025 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:2010533 , PMID:8567671 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:7818530 , PMID:8858123 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:8096693 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:8135797 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:25741868 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1562620 , PMID:1752947 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:8486765 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1512512 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:11334614 more ... familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1752947 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:8325986 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:24291057 more ... familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:11134145 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Familial Lipoprotein Lipase Deficiency ClinVar PMID:10735636 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:9225235 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:2349938 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1505655 more ... familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:22923420 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Lipase D deficiency ClinVar PMID:1731801 more ... familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1400331 familial lipoprotein lipase deficiency ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperlipoproteinemia, type I ClinVar PMID:1400331 , PMID:8325986 genetic disease ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:22239554 more ... Hyperapobetalipoproteinemia ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperapobetalipoproteinemia ClinVar PMID:10364086 more ... Hyperapobetalipoproteinemia ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperapobetalipoproteinemia ClinVar PMID:11334614 more ... Hyperapobetalipoproteinemia ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperapobetalipoproteinemia ClinVar Hyperapobetalipoproteinemia ISS RGD:12536618 9068941 ClinVar Annotator: match by term: Hyperapobetalipoproteinemia ClinVar PMID:25741868 , PMID:8541837
Gene-Chemical Interaction Annotations
