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Gene: ITCH (itchy E3 ubiquitin protein ligase) Sus scrofa
Symbol: ITCH
Name: itchy E3 ubiquitin protein ligase
CRRD ID: 13960314
Description: ENCODES a protein that exhibits ubiquitin-protein transferase activity (ortholog); INVOLVED IN negative regulation of alpha-beta T cell proliferation (inferred); negative regulation of apoptotic process (inferred); negative regulation of defense response to virus (inferred); PARTICIPATES IN Notch signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH cerebellar ataxia (ortholog); long QT syndrome (ortholog); Multisystem Autoimmune Disease with Facial Dysmorphism (ortholog); FOUND IN cytoplasmic vesicle (ortholog); early endosome (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: ncrna
RefSeq Status: MODEL
Homo sapiens (human) : ITCH (itchy E3 ubiquitin protein ligase)  HGNC  Alliance
Mus musculus (house mouse) : Itch (itchy, E3 ubiquitin protein ligase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itch (itchy E3 ubiquitin protein ligase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itch (itchy E3 ubiquitin protein ligase)
Pan paniscus (bonobo/pygmy chimpanzee) : ITCH (itchy E3 ubiquitin protein ligase)
Canis lupus familiaris (dog) : ITCH (itchy E3 ubiquitin protein ligase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itch (itchy E3 ubiquitin protein ligase)
Chlorocebus sabaeus (African green monkey) : ITCH (itchy E3 ubiquitin protein ligase)
Heterocephalus glaber (naked mole-rat) : Itch (itchy E3 ubiquitin protein ligase)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl1737,810,183 - 37,918,208 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11737,810,113 - 37,918,963 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21742,398,530 - 42,404,580 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on ITCH
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 13960314
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-02-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.