P4HA2 (prolyl 4-hydroxylase subunit alpha 2) - Chinchilla Research Resource Database
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Gene: P4HA2 (prolyl 4-hydroxylase subunit alpha 2) Sus scrofa
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Symbol: P4HA2
Name: prolyl 4-hydroxylase subunit alpha 2
CRRD ID: 13963158
Description: ENCODES a protein that exhibits iron ion binding (inferred); L-ascorbic acid binding (inferred); oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (inferred); INVOLVED IN oxidation-reduction process (inferred); peptidyl-proline hydroxylation (inferred); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); Myopia 25, Autosomal Dominant (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); procollagen-proline 4-dioxygenase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: prolyl 4-hydroxylase subunit alpha-2
Orthologs:
Homo sapiens (human) : P4HA2 (prolyl 4-hydroxylase subunit alpha 2)  HGNC  Alliance
Mus musculus (house mouse) : P4ha2 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : P4ha2 (prolyl 4-hydroxylase subunit alpha 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P4ha2 (prolyl 4-hydroxylase subunit alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : P4HA2 (prolyl 4-hydroxylase subunit alpha 2)
Canis lupus familiaris (dog) : P4HA2 (prolyl 4-hydroxylase subunit alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P4ha2 (prolyl 4-hydroxylase subunit alpha 2)
Chlorocebus sabaeus (African green monkey) : P4HA2 (prolyl 4-hydroxylase subunit alpha 2)
Heterocephalus glaber (naked mole-rat) : P4ha2 (prolyl 4-hydroxylase subunit alpha 2)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2134,502,210 - 134,595,430 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12134,502,210 - 134,595,444 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22139,853,792 - 139,886,023 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
P4HA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2134,502,210 - 134,595,430 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12134,502,210 - 134,595,444 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22139,853,792 - 139,886,023 (-)NCBISscrofa10.2Sscrofa10.2susScr3
P4HA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5132,191,838 - 132,295,315 (-)EnsemblGRCh38hg38GRCh38
GRCh385132,190,147 - 132,227,853 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,528,299 - 131,563,556 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,556,202 - 131,591,455 (-)NCBINCBI36hg18NCBI36
Build 345131,556,201 - 131,590,458NCBI
Celera5127,658,410 - 127,693,660 (-)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5126,720,651 - 126,756,017 (-)NCBIHuRef
CHM1_15130,961,055 - 130,996,320 (-)NCBICHM1_1
P4ha2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,991,750 - 54,022,494 (+)NCBI
GRCm381154,100,924 - 54,131,668 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1154,100,095 - 54,131,665 (+)EnsemblGRCm38mm10GRCm38
MGSCv371153,914,426 - 53,945,169 (+)NCBIGRCm37mm9NCBIm37
MGSCv361153,944,939 - 53,975,071 (+)NCBImm8
Celera1158,688,554 - 58,719,297 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1132.13NCBI
P4ha2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01039,435,227 - 39,464,134 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1039,435,227 - 39,464,188 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01039,214,791 - 39,243,698 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,522,157 - 39,551,063 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,535,833 - 39,564,271 (+)NCBI
Celera1037,584,460 - 37,613,368 (+)NCBICelera
Cytogenetic Map10q22NCBI
P4ha2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554083,574,860 - 3,607,015 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554083,574,860 - 3,607,015 (-)NCBIChiLan1.0ChiLan1.0
P4HA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15133,778,520 - 133,813,779 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5133,778,520 - 133,813,779 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05127,613,037 - 127,650,647 (-)NCBIMhudiblu_PPA_v0panPan3
P4HA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1120,514,978 - 20,549,541 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11120,514,982 - 20,548,261 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
P4ha2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366472,930,748 - 2,963,168 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
P4HA2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl2335,020,535 - 35,058,009 (-)Ensembl
ChlSab1.12335,022,675 - 35,058,128 (-)NCBI
P4ha2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473339,871,156 - 39,902,266 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2
Low 10 4 3 5 2 19 2 1 3
Below cutoff 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003354272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005661636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005661638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013995105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013995106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013995107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013995109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013995110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021085440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002342093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK391213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU406996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01013787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000043347   ⟹   ENSSSCP00000051977
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2134,502,210 - 134,537,584 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000047498   ⟹   ENSSSCP00000044447
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2134,502,213 - 134,595,430 (-)Ensembl
RefSeq Acc Id: XM_003354272   ⟹   XP_003354320
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,534,448 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005661636   ⟹   XP_005661693
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,534,198 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005661638   ⟹   XP_005661695
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,534,448 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013995105   ⟹   XP_013850559
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,534,198 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013995106   ⟹   XP_013850560
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,534,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013995107   ⟹   XP_013850561
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,533,861 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013995109   ⟹   XP_013850563
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,534,207 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013995110   ⟹   XP_013850564
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,533,543 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085434   ⟹   XP_020941093
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,595,434 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085435   ⟹   XP_020941094
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,595,434 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085436   ⟹   XP_020941095
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,595,434 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085437   ⟹   XP_020941096
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,595,433 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085438   ⟹   XP_020941097
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,595,444 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085439   ⟹   XP_020941098
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,571,122 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085440   ⟹   XP_020941099
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,533,609 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002342093
RefSeq Status:
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12134,502,210 - 134,534,215 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020941097   ⟸   XM_021085438
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020941094   ⟸   XM_021085435
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020941095   ⟸   XM_021085436
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020941093   ⟸   XM_021085434
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020941096   ⟸   XM_021085437
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020941098   ⟸   XM_021085439
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003354320   ⟸   XM_003354272
- Peptide Label: isoform X1
- UniProtKB: I3L769 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005661695   ⟸   XM_005661638
- Peptide Label: isoform X2
- UniProtKB: I3L5Y0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013850563   ⟸   XM_013995109
- Peptide Label: isoform X2
- UniProtKB: I3L5Y0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013850559   ⟸   XM_013995105
- Peptide Label: isoform X1
- UniProtKB: I3L769 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005661693   ⟸   XM_005661636
- Peptide Label: isoform X1
- UniProtKB: I3L769 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013850560   ⟸   XM_013995106
- Peptide Label: isoform X1
- UniProtKB: I3L769 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013850561   ⟸   XM_013995107
- Peptide Label: isoform X1
- UniProtKB: I3L769 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941099   ⟸   XM_021085440
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013850564   ⟸   XM_013995110
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSSSCP00000044447   ⟸   ENSSSCT00000047498
RefSeq Acc Id: ENSSSCP00000051977   ⟸   ENSSSCT00000043347
Protein Domains
Fe2OG dioxygenase   TPR_REGION


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000020915 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070018989 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000044447 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000051977 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070031766 UniProtKB/TrEMBL
  ENSSSCP00070031776 UniProtKB/TrEMBL
  ENSSSCP00070031783 UniProtKB/TrEMBL
  ENSSSCP00070031799 UniProtKB/TrEMBL
  ENSSSCP00070031804 UniProtKB/TrEMBL
  ENSSSCP00070031808 UniProtKB/TrEMBL
  ENSSSCP00070031833 UniProtKB/TrEMBL
  ENSSSCP00070031849 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000043347 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000047498 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070037971 UniProtKB/TrEMBL
  ENSSSCT00070037983 UniProtKB/TrEMBL
  ENSSSCT00070037991 UniProtKB/TrEMBL
  ENSSSCT00070038010 UniProtKB/TrEMBL
  ENSSSCT00070038015 UniProtKB/TrEMBL
  ENSSSCT00070038019 UniProtKB/TrEMBL
  ENSSSCT00070038049 UniProtKB/TrEMBL
  ENSSSCT00070038066 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro Oxoglu/Fe-dep_dioxygenase UniProtKB/TrEMBL
  Pro_4_hyd_alph UniProtKB/TrEMBL
  Pro_4_hyd_alph_N UniProtKB/TrEMBL
  TPR-contain_dom UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
KEGG Report ssc:100623801 UniProtKB/TrEMBL
NCBI Gene P4HA2 ENTREZGENE
Pfam 2OG-FeII_Oxy_3 UniProtKB/TrEMBL
  P4Ha_N UniProtKB/TrEMBL
PROSITE FE2OG_OXY UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
  TPR_REGION UniProtKB/TrEMBL
SMART P4Hc UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniGene Ssc.16984 ENTREZGENE
UniProt A0A287B6Q3_PIG UniProtKB/TrEMBL
  A0A4X1UQU2_PIG UniProtKB/TrEMBL
  A0A4X1UR01_PIG UniProtKB/TrEMBL
  A0A4X1UT02_PIG UniProtKB/TrEMBL
  I3L5Y0 ENTREZGENE, UniProtKB/TrEMBL
  I3L769 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91133 ENTREZGENE