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Gene: SIRT1 (sirtuin 1) Sus scrofa
Symbol: SIRT1
Name: sirtuin 1
CRRD ID: 13966638
Description: ENCODES a protein that exhibits caspase binding; deacetylase activity (ortholog); enzyme binding (ortholog); INVOLVED IN intrinsic apoptotic signaling pathway; mitochondrion organization; negative regulation of adipose tissue development; PARTICIPATES IN histone modification pathway; hypoxia inducible factor pathway; p53 signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN cytoplasm; nucleus; axon (ortholog); INTERACTS WITH nicotinamide; resveratrol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: NAD-dependent deacetylase sirtuin 1; NAD-dependent protein deacetylase sirtuin-1; sirtuin1
Homo sapiens (human) : SIRT1 (sirtuin 1)  HGNC  Alliance
Mus musculus (house mouse) : Sirt1 (sirtuin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sirt1 (sirtuin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sirt1 (sirtuin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIRT1 (sirtuin 1)
Canis lupus familiaris (dog) : SIRT1 (sirtuin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sirt1 (sirtuin 1)
Chlorocebus sabaeus (African green monkey) : SIRT1 (sirtuin 1)
Heterocephalus glaber (naked mole-rat) : Sirt1 (sirtuin 1)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl1471,091,157 - 71,123,299 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11471,091,167 - 71,126,351 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21477,182,651 - 77,184,716 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21477,053,991 - 77,079,850 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on SIRT1
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 13966638
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-07-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.