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Gene: ABCB4 (ATP binding cassette subfamily B member 4) Sus scrofa
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Symbol: ABCB4
Name: ATP binding cassette subfamily B member 4
CRRD ID: 14031420
Description: ENCODES a protein that exhibits ATP binding (inferred); ATPase activity (inferred); ATPase-coupled transmembrane transporter activity (inferred); INVOLVED IN bile acid secretion (ortholog); cellular response to bile acid (ortholog); lipid homeostasis (ortholog); PARTICIPATES IN multidrug resistance protein mediated transport pathway; ASSOCIATED WITH acalculous cholecystitis (ortholog); Animal Disease Models (ortholog); atrial heart septal defect 1 (ortholog); FOUND IN actin cytoskeleton (ortholog); apical plasma membrane (ortholog); cytoplasm (ortholog); INTERACTS WITH 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile; 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one; itraconazole
Type: protein-coding
RefSeq Status: MODEL
Also known as: ATP-binding cassette, sub-family B (MDR/TAP), member 4; MDR3; multidrug resistance 3; P-glycoprotein class III; Pgp3; phosphatidylcholine translocator ABCB4
Orthologs:
Homo sapiens (human) : ABCB4 (ATP binding cassette subfamily B member 4)  HGNC  Alliance
Mus musculus (house mouse) : Abcb4 (ATP-binding cassette, sub-family B (MDR/TAP), member 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Abcb4 (ATP binding cassette subfamily B member 4)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ABCB4 (ATP binding cassette subfamily B member 4)
Canis lupus familiaris (dog) : ABCB4 (ATP binding cassette subfamily B member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcb4 (ATP binding cassette subfamily B member 4)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1993,171,371 - 93,262,124 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29102,651,665 - 102,741,039 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

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More on ABCB4
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 14031420
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.