TIGAR (TP53 induced glycolysis regulatory phosphatase) - Chinchilla Research Resource Database
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Gene: TIGAR (TP53 induced glycolysis regulatory phosphatase) Sus scrofa
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Symbol: TIGAR
Name: TP53 induced glycolysis regulatory phosphatase
CRRD ID: 14085279
Description: INVOLVED IN cellular response to cobalt ion (inferred); cellular response to DNA damage stimulus (inferred); cellular response to hypoxia (inferred); ASSOCIATED WITH Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: C5H12orf5; fructose-2,6-bisphosphatase TIGAR
Orthologs:
Homo sapiens (human) : TIGAR (TP53 induced glycolysis regulatory phosphatase)  HGNC  Alliance
Mus musculus (house mouse) : Tigar (Trp53 induced glycolysis regulatory phosphatase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tigar (TP53 induced glycolysis regulatory phosphatase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tigar (TP53 induced glycolysis regulatory phosphatase)
Pan paniscus (bonobo/pygmy chimpanzee) : TIGAR (TP53 induced glycolysis regulatory phosphatase)
Canis lupus familiaris (dog) : TIGAR (TP53 induced glycolysis regulatory phosphatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tigar (TP53 induced glycolysis regulatory phosphatase)
Chlorocebus sabaeus (African green monkey) : TIGAR (TP53 induced glycolysis regulatory phosphatase)
Heterocephalus glaber (naked mole-rat) : Tigar (TP53 induced glycolysis regulatory phosphatase)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl566,044,686 - 66,067,377 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1566,044,679 - 66,067,571 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2568,266,609 - 68,289,947 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
TIGAR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl566,044,686 - 66,067,377 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1566,044,679 - 66,067,571 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2568,266,609 - 68,289,947 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TIGAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl124,307,763 - 4,360,028 (+)EnsemblGRCh38hg38GRCh38
GRCh38124,321,213 - 4,360,028 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37124,430,359 - 4,469,194 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,300,620 - 4,339,455 (+)NCBINCBI36hg18NCBI36
Build 34124,300,631 - 4,332,599NCBI
Celera126,052,425 - 6,091,264 (+)NCBI
Cytogenetic Map12p13.32NCBI
HuRef124,287,018 - 4,325,825 (+)NCBIHuRef
CHM1_1124,429,992 - 4,468,805 (+)NCBICHM1_1
Tigar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396127,062,079 - 127,086,564 (-)NCBI
GRCm386127,085,116 - 127,109,552 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6127,085,116 - 127,109,557 (-)EnsemblGRCm38mm10GRCm38
MGSCv376127,035,134 - 127,059,570 (-)NCBIGRCm37mm9NCBIm37
MGSCv366127,984,031 - 128,005,972 (-)NCBImm8
MGSCv366127,052,982 - 127,075,160 (-)NCBImm8
Celera6128,766,834 - 128,786,116 (-)NCBICelera
Cytogenetic Map6F3NCBI
Tigar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04159,635,145 - 159,654,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4159,635,153 - 159,654,063 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04231,948,786 - 231,966,869 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44163,481,393 - 163,502,412 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4148,642,195 - 148,661,115 (-)NCBICelera
Cytogenetic Map4q42NCBI
Tigar
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554132,129,678 - 2,154,380 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554132,129,719 - 2,153,873 (+)NCBIChiLan1.0ChiLan1.0
TIGAR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1124,353,272 - 4,386,758 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl124,353,272 - 4,385,380 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0124,429,945 - 4,462,142 (+)NCBIMhudiblu_PPA_v0panPan3
TIGAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2740,523,314 - 40,549,332 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12740,521,751 - 40,549,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tigar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366064,518,525 - 4,540,109 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIGAR
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl114,355,053 - 4,381,273 (+)Ensembl
ChlSab1.1114,354,911 - 4,381,762 (+)NCBI
Tigar
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248601,416,419 - 1,455,953 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 6
Low 10 4 3 5 2 17 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000028356   ⟹   ENSSSCP00000021128
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl566,044,686 - 66,067,377 (-)Ensembl
RefSeq Acc Id: XM_005655710   ⟹   XP_005655767
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1566,044,679 - 66,067,571 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021092447   ⟹   XP_020948106
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1566,044,679 - 66,067,213 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002344132
RefSeq Status:
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1566,044,679 - 66,067,355 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005655767 (Get FASTA)   NCBI Sequence Viewer  
  XP_020948106 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005655767   ⟸   XM_005655710
- Peptide Label: isoform X2
- UniProtKB: F1SKZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020948106   ⟸   XM_021092447
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSSCP00000021128   ⟸   ENSSSCT00000028356


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024219 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070018608 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000021128 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070030675 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000028356 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070036690 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1240 UniProtKB/TrEMBL
InterPro His_Pase_superF_clade-1 UniProtKB/TrEMBL
  His_PPase_superfam UniProtKB/TrEMBL
  PG/BPGM_mutase_AS UniProtKB/TrEMBL
KEGG Report ssc:100154112 UniProtKB/TrEMBL
NCBI Gene TIGAR ENTREZGENE
Pfam His_Phos_1 UniProtKB/TrEMBL
PROSITE PG_MUTASE UniProtKB/TrEMBL
SMART PGAM UniProtKB/TrEMBL
Superfamily-SCOP SSF53254 UniProtKB/TrEMBL
UniGene Ssc.48913 ENTREZGENE
UniProt A0A4X1UQ65_PIG UniProtKB/TrEMBL
  F1SKZ0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:93980 ENTREZGENE