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Gene: MLH1 (mutL homolog 1) Sus scrofa
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Symbol: MLH1
Name: mutL homolog 1
Description: ENCODES a protein that exhibits ATP binding (inferred); ATPase activity (inferred); chromatin binding (inferred); INVOLVED IN double-strand break repair via nonhomologous end joining (inferred); female meiosis chromosome segregation (inferred); intrinsic apoptotic signaling pathway in response to DNA damage (inferred); PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; endometrial cancer pathway; ASSOCIATED WITH Breast Cancer, Familial (ortholog); cervix uteri carcinoma in situ (ortholog); colon cancer (ortholog); FOUND IN late recombination nodule (inferred); male germ cell nucleus (inferred); mismatch repair complex (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA mismatch repair protein Mlh1; mutL homolog 1, colon cancer, nonpolyposis type 2; mutL-like protein 1
Orthologs:
Homo sapiens (human) : MLH1 (mutL homolog 1)  HGNC  Alliance
Mus musculus (house mouse) : Mlh1 (mutL homolog 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mlh1 (mutL homolog 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mlh1 (mutL homolog 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MLH1 (mutL homolog 1)
Canis lupus familiaris (dog) : MLH1 (mutL homolog 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mlh1 (mutL homolog 1)
Chlorocebus sabaeus (African green monkey) : MLH1 (mutL homolog 1)
Heterocephalus glaber (naked mole-rat) : Mlh1 (mutL homolog 1)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1321,791,201 - 21,877,757 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11321,791,276 - 21,877,789 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21323,613,450 - 23,692,364 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on MLH1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 14187856
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.