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Gene: IRS1 (insulin receptor substrate 1) Sus scrofa
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Symbol: IRS1
Name: insulin receptor substrate 1
CRRD ID: 14279689
Description: ENCODES a protein that exhibits protein domain specific binding (ortholog); protein kinase binding (ortholog); protein kinase C binding (ortholog); INVOLVED IN aging (ortholog); cellular response to angiotensin (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); PARTICIPATES IN insulin signaling pathway; insulin-like growth factor signaling pathway; interleukin-2 signaling pathway; ASSOCIATED WITH AIDS Dementia Complex (ortholog); Alzheimer's disease (ortholog); coronary artery disease (ortholog); FOUND IN ciliary basal body (ortholog); cytoplasm (ortholog); insulin receptor complex (ortholog); INTERACTS WITH dexamethasone; resveratrol
Type: protein-coding
RefSeq Status: PROVISIONAL
Orthologs:
Homo sapiens (human) : IRS1 (insulin receptor substrate 1)  HGNC  Alliance
Mus musculus (house mouse) : Irs1 (insulin receptor substrate 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Irs1 (insulin receptor substrate 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irs1 (insulin receptor substrate 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IRS1 (insulin receptor substrate 1)
Canis lupus familiaris (dog) : IRS1 (insulin receptor substrate 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irs1 (insulin receptor substrate 1)
Chlorocebus sabaeus (African green monkey) : IRS1 (insulin receptor substrate 1)
Heterocephalus glaber (naked mole-rat) : Irs1 (insulin receptor substrate 1)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15128,245,846 - 128,308,335 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115128,245,846 - 128,307,321 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215142,086,134 - 142,147,797 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on IRS1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 14279689
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.