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Gene: CYP51 (cytochrome P450, family 51, subfamily A, polypeptide 1) Sus scrofa
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Symbol: CYP51
Name: cytochrome P450, family 51, subfamily A, polypeptide 1
Description: ENCODES a protein that exhibits heme binding (inferred); iron ion binding (inferred); monooxygenase activity (inferred); INVOLVED IN demethylation (inferred); negative regulation of amyloid-beta clearance (inferred); negative regulation of protein catabolic process (inferred); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH Hypercholesterolemia (ortholog); long QT syndrome (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); integral component of membrane (inferred); INTERACTS WITH ethanol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CYP51A1; CYPLI; cytochrome P450 51; cytochrome P450 51A1; cytochrome P450-14DM; cytochrome P45014DM; cytochrome P450LI; lanosterol 14-alpha demethylase; lanosterol 14-demethylase; LDM; sterol 14-alpha demethylase
Orthologs:
Homo sapiens (human) : CYP51A1 (cytochrome P450 family 51 subfamily A member 1)  HGNC  Alliance
Mus musculus (house mouse) : Cyp51 (cytochrome P450, family 51)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cyp51 (cytochrome P450, family 51)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102027002 (lanosterol 14-alpha demethylase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100985833 (lanosterol 14-alpha demethylase)
Canis lupus familiaris (dog) : CYP51A1 (cytochrome P450 family 51 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101955024 (lanosterol 14-alpha demethylase)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1972,057,506 - 72,079,587 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2978,792,905 - 78,814,951 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9 NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on CYP51
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 14296496
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.