Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tmem67wpk (transmembrane protein 67; wpk mutant) Rattus norvegicus
Analyze
Symbol: Tmem67wpk
Name: transmembrane protein 67; wpk mutant
Description: A single C to T substitution in exon 12 was identified as the mutated allele in the Wpk rat. This mutation converts a proline to a leucine in the protein products(P394L). This mutation was not present in the parental Wistar strain.
INVOLVED IN head development; ASSOCIATED WITH abnormal blood-cerebrospinal fluid barrier function; abnormal cerebrospinal fluid flow; abnormal head shape; ASSOCIATED WITH autosomal recessive polycystic kidney disease; communicating hydrocephalus; hydrocephalus
Type: allele  of Tmem67  
Is Marker For: Strains:   Wpk   Wpk +/-   Wpk -/-  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position: No map positions available.


Disease Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated

Genomics

Related Rat Strains

Expression


Sequence

Nucleotide Sequences

Additional Information

 
More on Tmem67wpk
Alliance Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 14995943
Created: 2019-11-01
Species: Rattus norvegicus
Last Modified: 2019-11-21
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.