Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Npl (N-acetylneuraminate pyruvate lyase) Rattus norvegicus
Analyze
Symbol: Npl
Name: N-acetylneuraminate pyruvate lyase
Description: Predicted to have N-acetylneuraminate lyase activity and identical protein binding activity. Predicted to be involved in N-acetylneuraminate catabolic process and carbohydrate metabolic process. Predicted to localize to the cytoplasm. Orthologous to human NPL (N-acetylneuraminate pyruvate lyase); PARTICIPATES IN amino sugar metabolic pathway; french type sialuria pathway; sialic acid storage disease pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 3',5'-cyclic AMP; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC304860; N-acetylneuraminate lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NALase; sialate lyase; sialate-pyruvate lyase; sialic acid aldolase; sialic acid lyase; similar to N-acetylneuraminate pyruvate lyase
Orthologs:
Homo sapiens (human) : NPL (N-acetylneuraminate pyruvate lyase)  HGNC  Alliance
Mus musculus (house mouse) : Npl (N-acetylneuraminate pyruvate lyase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npl (N-acetylneuraminate pyruvate lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : NPL (N-acetylneuraminate pyruvate lyase)
Canis lupus familiaris (dog) : NPL (N-acetylneuraminate pyruvate lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npl (N-acetylneuraminate pyruvate lyase)
Sus scrofa (pig) : NPL (N-acetylneuraminate pyruvate lyase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01370,938,073 - 70,981,179 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1370,938,082 - 70,980,913 (-)Ensembl
Rnor_5.01375,903,277 - 75,946,223 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41368,524,023 - 68,567,312 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1365,558,454 - 65,600,109 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Npl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1549702
Created: 2005-09-15
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.