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Gene: Hprt (hypoxanthine guanine phosphoribosyl transferase) Mus musculus
Symbol: Hprt
Name: hypoxanthine guanine phosphoribosyl transferase
CRRD ID: 1549982
Description: Exhibits hypoxanthine phosphoribosyltransferase activity and identical protein binding activity. Involved in several processes, including grooming behavior; nervous system development; and purine-containing compound salvage. Localizes to cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study Lesch-Nyhan syndrome. Human ortholog(s) of this gene implicated in Lesch-Nyhan syndrome. Orthologous to human HPRT1 (hypoxanthine phosphoribosyltransferase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C81579; HGPRT; HGPRTase; HPGRT; Hpr; HPRT B; Hprt1; hypoxanthine guanine phosphoribosyl transferase 1; hypoxanthine-guanine phosphoribosyltransferase; MGC103149
Homo sapiens (human) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hprt1 (hypoxanthine phosphoribosyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hprt1 (hypoxanthine phosphoribosyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)
Canis lupus familiaris (dog) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hprt1 (hypoxanthine phosphoribosyltransferase 1)
Sus scrofa (pig) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)
Chlorocebus sabaeus (African green monkey) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Hprt1 (hypoxanthine phosphoribosyltransferase 1)
more info ...
Related Pseudogenes: Gm18992   Hprt-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39X52,076,955 - 52,110,537 (+)NCBI
GRCm38X52,988,078 - 53,021,660 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX52,988,137 - 53,021,659 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X50,341,255 - 50,374,837 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X49,232,764 - 49,266,286 (+)NCBImm8
CeleraX40,414,095 - 40,447,630 (+)NCBICelera
Cytogenetic MapXA5NCBI
cM MapX29.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hprt
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1549982
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.