Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Hprt (hypoxanthine guanine phosphoribosyl transferase) Mus musculus
Analyze
Symbol: Hprt
Name: hypoxanthine guanine phosphoribosyl transferase
Description: Exhibits hypoxanthine phosphoribosyltransferase activity and identical protein binding activity. Involved in several processes, including grooming behavior; nervous system development; and purine-containing compound salvage. Localizes to the cytoplasm. Used to study Lesch-Nyhan syndrome. Human ortholog(s) of this gene implicated in Lesch-Nyhan syndrome. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human HPRT1 (hypoxanthine phosphoribosyltransferase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C81579; HGPRT; HGPRTase; HPGRT; HPRT B; Hprt1; hypoxanthine guanine phosphoribosyl transferase 1; hypoxanthine-guanine phosphoribosyltransferase; MGC103149
Orthologs:
Homo sapiens (human) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hprt1 (hypoxanthine phosphoribosyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hprt1 (hypoxanthine phosphoribosyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)
Canis lupus familiaris (dog) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hprt1 (hypoxanthine phosphoribosyltransferase 1)
Sus scrofa (pig) : HPRT1 (hypoxanthine phosphoribosyltransferase 1)
more info ...
Related Pseudogenes: Gm18992  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38X52,988,078 - 53,021,660 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X50,341,255 - 50,374,837 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X49,232,764 - 49,266,286 (+)NCBImm8
CeleraX40,414,095 - 40,447,630 (+)NCBICelera
Cytogenetic MapX A5NCBI
cM MapX29.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hprt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1549982
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.