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Gene: Tlr9 (toll-like receptor 9) Mus musculus
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Symbol: Tlr9
Name: toll-like receptor 9
Description: Predicted to have interleukin-1 receptor binding activity; nucleic acid binding activity; and signaling pattern recognition receptor activity. Involved in several processes, including positive regulation of cytokine production; regulation of defense response; and regulation of macromolecule biosynthetic process. Localizes to the cytoplasmic vesicle; endoplasmic reticulum; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including allergic bronchopulmonary aspergillosis; cystic fibrosis; glomerulonephritis (multiple); lung disease (multiple); and systemic lupus erythematosus. Is expressed in intestine and small intestine mucosa. Orthologous to human TLR9 (toll like receptor 9); PARTICIPATES IN Toll-like receptor signaling pathway; Chagas disease pathway; malaria pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Orthologs:
Homo sapiens (human) : TLR9 (toll like receptor 9)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tlr9 (toll-like receptor 9)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlr9 (toll like receptor 9)
Canis lupus familiaris (dog) : TLR9 (toll like receptor 9)
Sus scrofa (pig) : TLR9 (toll like receptor 9)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389106,222,598 - 106,226,876 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379106,124,929 - 106,129,207 (+)NCBIGRCm37mm9NCBIm37
MGSCv369106,080,699 - 106,084,977 (+)NCBImm8
Celera9105,848,890 - 105,853,167 (+)NCBICelera
Cytogenetic Map9 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tlr9
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1549988
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.