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Gene: Sharpin (SHANK-associated RH domain interacting protein) Mus musculus
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Symbol: Sharpin
Name: SHANK-associated RH domain interacting protein
CRRD ID: 1549996
Description: Predicted to have identical protein binding activity and polyubiquitin modification-dependent protein binding activity. Involved in several processes, including apoptotic nuclear changes; keratinization; and regulation of signal transduction. Predicted to localize to several cellular components, including LUBAC complex; dendrite; and postsynaptic density. Is expressed in genitourinary system. Used to study atopic dermatitis. Orthologous to human SHARPIN (SHANK associated RH domain interactor); PARTICIPATES IN integrin mediated signaling pathway; nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610041B22Rik; AW121341; cpd; cpdm; mSIPL1; protein kinase C-interacting protein RBCC like 1; RBCKL1; S; shank-associated RH domain-interacting protein; shank-interacting protein-like 1; SIPL1
Orthologs:
Homo sapiens (human) : SHARPIN (SHANK associated RH domain interactor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sharpin (SHANK-associated RH domain interactor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sharpin (SHANK associated RH domain interactor)
Pan paniscus (bonobo/pygmy chimpanzee) : SHARPIN (SHANK associated RH domain interactor)
Canis lupus familiaris (dog) : SHARPIN (SHANK associated RH domain interactor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sharpin (SHANK associated RH domain interactor)
Sus scrofa (pig) : SHARPIN (SHANK associated RH domain interactor)
Chlorocebus sabaeus (African green monkey) : SHARPIN (SHANK associated RH domain interactor)
Heterocephalus glaber (naked mole-rat) : Sharpin (SHANK associated RH domain interactor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1576,347,040 - 76,351,111 (-)EnsemblGRCm38mm10GRCm38
GRCm381576,347,040 - 76,351,110 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371576,177,470 - 76,181,540 (-)NCBIGRCm37mm9NCBIm37
MGSCv361576,174,295 - 76,178,352 (-)NCBImm8
Celera1577,847,101 - 77,851,171 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sharpin
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1549996
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.