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Gene: Sharpin (SHANK-associated RH domain interacting protein) Mus musculus
Symbol: Sharpin
Name: SHANK-associated RH domain interacting protein
CRRD ID: 1549996
Description: Predicted to have identical protein binding activity and polyubiquitin modification-dependent protein binding activity. Involved in several processes, including apoptotic nuclear changes; keratinization; and regulation of signal transduction. Predicted to localize to several cellular components, including LUBAC complex; dendrite; and postsynaptic density. Is expressed in genitourinary system. Used to study atopic dermatitis. Orthologous to human SHARPIN (SHANK associated RH domain interactor); PARTICIPATES IN integrin mediated signaling pathway; nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610041B22Rik; AW121341; cpd; cpdm; mSIPL1; protein kinase C-interacting protein RBCC like 1; RBCKL1; S; shank-associated RH domain-interacting protein; shank-interacting protein-like 1; SIPL1
Homo sapiens (human) : SHARPIN (SHANK associated RH domain interactor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sharpin (SHANK-associated RH domain interactor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sharpin (SHANK associated RH domain interactor)
Pan paniscus (bonobo/pygmy chimpanzee) : SHARPIN (SHANK associated RH domain interactor)
Canis lupus familiaris (dog) : SHARPIN (SHANK associated RH domain interactor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sharpin (SHANK associated RH domain interactor)
Sus scrofa (pig) : SHARPIN (SHANK associated RH domain interactor)
Chlorocebus sabaeus (African green monkey) : SHARPIN (SHANK associated RH domain interactor)
Heterocephalus glaber (naked mole-rat) : Sharpin (SHANK associated RH domain interactor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1576,347,040 - 76,351,111 (-)EnsemblGRCm38mm10GRCm38
GRCm381576,347,040 - 76,351,110 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371576,177,470 - 76,181,540 (-)NCBIGRCm37mm9NCBIm37
MGSCv361576,174,295 - 76,178,352 (-)NCBImm8
Celera1577,847,101 - 77,851,171 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sharpin
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1549996
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.