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Gene: Icmt (isoprenylcysteine carboxyl methyltransferase) Mus musculus
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Symbol: Icmt
Name: isoprenylcysteine carboxyl methyltransferase
Description: Exhibits cAMP response element binding protein binding activity and protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity. Involved in several processes, including TOR signaling; determination of adult lifespan; and growth. Predicted to localize to the endoplasmic reticulum and membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human ICMT (isoprenylcysteine carboxyl methyltransferase); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700008E11Rik; C80758; Gm13095; HSTE14; MGC118506; pcCMT; PPMT; prenylated protein carboxyl methyltransferase; prenylcysteine carboxyl methyltransferase; protein-S isoprenylcysteine O-methyltransferase; protein-S-isoprenylcysteine O-methyltransferase; STE14
Orthologs:
Homo sapiens (human) : ICMT (isoprenylcysteine carboxyl methyltransferase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Icmt (isoprenylcysteine carboxyl methyltransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Icmt (isoprenylcysteine carboxyl methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : ICMT (isoprenylcysteine carboxyl methyltransferase)
Canis lupus familiaris (dog) : ICMT (isoprenylcysteine carboxyl methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Icmt (isoprenylcysteine carboxyl methyltransferase)
Sus scrofa (pig) : ICMT (isoprenylcysteine carboxyl methyltransferase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384152,297,214 - 152,307,126 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374151,671,460 - 151,681,231 (+)NCBIGRCm37mm9NCBIm37
MGSCv364151,141,151 - 151,150,922 (+)NCBImm8
Celera4154,584,546 - 154,594,458 (+)NCBICelera
Cytogenetic Map4 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Icmt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550037
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.