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Gene: Mapk7 (mitogen-activated protein kinase 7) Mus musculus
Symbol: Mapk7
Name: mitogen-activated protein kinase 7
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including negative regulation of intracellular signal transduction; peptidyl-serine phosphorylation; and regulation of angiogenesis. Localizes to cytosol and nucleus. Is expressed in several structures, including cardiovascular system; early conceptus; ganglia; genitourinary system; and salivary gland. Orthologous to human MAPK7 (mitogen-activated protein kinase 7); PARTICIPATES IN altered Erk5 MAPK signaling pathway; Erk5 MAPK signaling pathway; gonadotropin-releasing hormone signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: b2b2346Clo; big MAP kinase 1; BMK-1; BMK1; ERK-5; ERK5; Erk5-T; extracellular signal regulated kinase 5; extracellular signal-regulated kinase 5; MAP kinase 7; MAPK 7; mitogen activated protein kinase 7; mitogen-activated kinase 7; PRKM7
Homo sapiens (human) : MAPK7 (mitogen-activated protein kinase 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mapk7 (mitogen-activated protein kinase 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk7 (mitogen-activated protein kinase 7)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK7 (mitogen-activated protein kinase 7)
Canis lupus familiaris (dog) : MAPK7 (mitogen-activated protein kinase 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk7 (mitogen-activated protein kinase 7)
Sus scrofa (pig) : MAPK7 (mitogen-activated protein kinase 7)
Chlorocebus sabaeus (African green monkey) : MAPK7 (mitogen-activated protein kinase 7)
Heterocephalus glaber (naked mole-rat) : Mapk7 (mitogen-activated protein kinase 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1161,488,812 - 61,494,406 (-)EnsemblGRCm38mm10GRCm38
GRCm381161,488,812 - 61,494,267 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371161,302,314 - 61,307,715 (-)NCBIGRCm37mm9NCBIm37
MGSCv361161,305,007 - 61,310,410 (-)NCBImm8
MGSCv361161,918,787 - 61,924,191 (-)NCBImm8
Cytogenetic Map11B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mapk7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550055
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.