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Gene: Mapk7 (mitogen-activated protein kinase 7) Mus musculus
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Symbol: Mapk7
Name: mitogen-activated protein kinase 7
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including negative regulation of intracellular signal transduction; peptidyl-serine phosphorylation; and regulation of angiogenesis. Localizes to cytosol and nucleus. Is expressed in several structures, including cardiovascular system; early conceptus; ganglia; genitourinary system; and salivary gland. Orthologous to human MAPK7 (mitogen-activated protein kinase 7); PARTICIPATES IN altered Erk5 MAPK signaling pathway; Erk5 MAPK signaling pathway; gonadotropin-releasing hormone signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: b2b2346Clo; big MAP kinase 1; BMK-1; BMK1; ERK-5; ERK5; Erk5-T; extracellular signal regulated kinase 5; extracellular signal-regulated kinase 5; MAP kinase 7; MAPK 7; mitogen activated protein kinase 7; mitogen-activated kinase 7; PRKM7
Orthologs:
Homo sapiens (human) : MAPK7 (mitogen-activated protein kinase 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mapk7 (mitogen-activated protein kinase 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk7 (mitogen-activated protein kinase 7)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK7 (mitogen-activated protein kinase 7)
Canis lupus familiaris (dog) : MAPK7 (mitogen-activated protein kinase 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk7 (mitogen-activated protein kinase 7)
Sus scrofa (pig) : MAPK7 (mitogen-activated protein kinase 7)
Chlorocebus sabaeus (African green monkey) : MAPK7 (mitogen-activated protein kinase 7)
Heterocephalus glaber (naked mole-rat) : Mapk7 (mitogen-activated protein kinase 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1161,488,812 - 61,494,406 (-)EnsemblGRCm38mm10GRCm38
GRCm381161,488,812 - 61,494,267 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371161,302,314 - 61,307,715 (-)NCBIGRCm37mm9NCBIm37
MGSCv361161,305,007 - 61,310,410 (-)NCBImm8
MGSCv361161,918,787 - 61,924,191 (-)NCBImm8
Cytogenetic Map11B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mapk7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550055
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.