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Gene: Lars (leucyl-tRNA synthetase) Mus musculus
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Symbol: Lars
Name: leucyl-tRNA synthetase
Description: Exhibits leucine-tRNA ligase activity. Involved in leucyl-tRNA aminoacylation. Localizes to aminoacyl-tRNA synthetase multienzyme complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeleton. Orthologous to human LARS1 (leucyl-tRNA synthetase 1); PARTICIPATES IN valine, leucine and isoleucine biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310045K21Rik; 3110009L02Rik; AW536573; Lars1; leucine--tRNA ligase; leucine--tRNA ligase, cytoplasmic; leucyl-tRNA synthetase, cytoplasmic; leuRS; mKIAA1352
Orthologs:
Homo sapiens (human) : LARS1 (leucyl-tRNA synthetase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lars1 (leucyl-tRNA synthetase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lars1 (leucyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LARS1 (leucyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : LARS1 (leucyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lars1 (leucyl-tRNA synthetase 1)
Sus scrofa (pig) : LARS1 (leucyl-tRNA synthetase 1)
Chlorocebus sabaeus (African green monkey) : LARS1 (leucyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Lars1 (leucyl-tRNA synthetase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1842,202,298 - 42,262,194 (-)EnsemblGRCm38mm10GRCm38
GRCm381842,202,298 - 42,262,237 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371842,362,003 - 42,421,725 (-)NCBIGRCm37mm9NCBIm37
MGSCv361842,328,271 - 42,388,167 (-)NCBImm8
Celera1843,563,719 - 43,623,468 (-)NCBICelera
Cytogenetic Map18B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lars
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550076
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.