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Gene: Clcf1 (cardiotrophin-like cytokine factor 1) Mus musculus
Symbol: Clcf1
Name: cardiotrophin-like cytokine factor 1
Description: Exhibits cytokine activity. Involved in several processes, including positive regulation of B cell activation; positive regulation of astrocyte differentiation; and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to localize to the CNTFR-CLCF1 complex and CRLF-CLCF1 complex. Human ortholog(s) of this gene implicated in cold-induced sweating syndrome 2. Is expressed in several structures, including alimentary system; central nervous system; lung; metanephros; and skeletal musculature. Orthologous to human CLCF1 (cardiotrophin like cytokine factor 1); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: b cell-stimulating factor 3; B-cell stimulating factor 3; B-cell-stimulating factor 3; BSF-3; Bsf3; CLC; MGC129162; MGC129163; neurotrophin-1/B-cell stimulating factor-3; NNT-1; NNT-1/BSF-3; novel neurotrophin-1
Homo sapiens (human) : CLCF1 (cardiotrophin like cytokine factor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Clcf1 (cardiotrophin-like cytokine factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clcf1 (cardiotrophin like cytokine factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCF1 (cardiotrophin like cytokine factor 1)
Canis lupus familiaris (dog) : CLCF1 (cardiotrophin like cytokine factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcf1 (cardiotrophin like cytokine factor 1)
Sus scrofa (pig) : CLCF1 (cardiotrophin like cytokine factor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38194,214,238 - 4,223,505 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37194,214,392 - 4,222,615 (+)NCBIGRCm37mm9NCBIm37
MGSCv36194,214,392 - 4,222,615 (+)NCBImm8
Celera194,085,708 - 4,093,967 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Clcf1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550082
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.