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Gene: Clcf1 (cardiotrophin-like cytokine factor 1) Mus musculus
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Symbol: Clcf1
Name: cardiotrophin-like cytokine factor 1
Description: Exhibits cytokine activity. Involved in several processes, including positive regulation of B cell activation; positive regulation of astrocyte differentiation; and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to localize to the CNTFR-CLCF1 complex and CRLF-CLCF1 complex. Human ortholog(s) of this gene implicated in cold-induced sweating syndrome 2. Is expressed in several structures, including alimentary system; central nervous system; lung; metanephros; and skeletal musculature. Orthologous to human CLCF1 (cardiotrophin like cytokine factor 1); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: b cell-stimulating factor 3; B-cell stimulating factor 3; B-cell-stimulating factor 3; BSF-3; Bsf3; CLC; MGC129162; MGC129163; neurotrophin-1/B-cell stimulating factor-3; NNT-1; NNT-1/BSF-3; novel neurotrophin-1
Orthologs:
Homo sapiens (human) : CLCF1 (cardiotrophin like cytokine factor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Clcf1 (cardiotrophin-like cytokine factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clcf1 (cardiotrophin like cytokine factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCF1 (cardiotrophin like cytokine factor 1)
Canis lupus familiaris (dog) : CLCF1 (cardiotrophin like cytokine factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcf1 (cardiotrophin like cytokine factor 1)
Sus scrofa (pig) : CLCF1 (cardiotrophin like cytokine factor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38194,214,238 - 4,223,505 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37194,214,392 - 4,222,615 (+)NCBIGRCm37mm9NCBIm37
MGSCv36194,214,392 - 4,222,615 (+)NCBImm8
Celera194,085,708 - 4,093,967 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Clcf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550082
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.