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Gene: Duox1 (dual oxidase 1) Mus musculus
Symbol: Duox1
Name: dual oxidase 1
Description: Predicted to have superoxide-generating NADPH oxidase activity. Involved in reactive oxygen species metabolic process. Localizes to the plasma membrane. Is expressed in brain; placenta; and thyroid gland. Orthologous to human DUOX1 (dual oxidase 1); PARTICIPATES IN thyroid hormone biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; apigenin; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9930101G15Rik; AW987690; dual oxidase 2; Duox2; LNOX1; LNOX2; NOXEF1; NOXEF2; P138-TOX; THOX1; THOX2
Homo sapiens (human) : DUOX1 (dual oxidase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Duox1 (dual oxidase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Duox1 (dual oxidase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DUOX1 (dual oxidase 1)
Canis lupus familiaris (dog) : DUOX1 (dual oxidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Duox1 (dual oxidase 1)
Sus scrofa (pig) : DUOX1 (dual oxidase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382122,313,010 - 122,347,972 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372122,141,408 - 122,173,708 (+)NCBIGRCm37mm9NCBIm37
MGSCv362123,286,960 - 123,321,338 (+)NCBImm8
MGSCv362122,005,116 - 122,039,413 (+)NCBImm8
Celera2123,465,585 - 123,497,811 (+)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Duox1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550105
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.