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Gene: Spcs1 (signal peptidase complex subunit 1 homolog (S. cerevisiae)) Mus musculus
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Symbol: Spcs1
Name: signal peptidase complex subunit 1 homolog (S. cerevisiae)
CRRD ID: 1550125
Description: Exhibits ribosome binding activity. Predicted to be involved in several processes, including protein targeting to ER; signal peptide processing; and viral protein processing. Predicted to localize to integral component of endoplasmic reticulum membrane and signal peptidase complex. Is expressed in several structures, including alimentary system; cranium; ear; integumental system; and nervous system. Orthologous to human SPCS1 (signal peptidase complex subunit 1); PARTICIPATES IN biotin metabolic pathway; biotinidase deficiency pathway; holocarboxylase synthetase deficiency pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810004F21Rik; microsomal signal peptidase 12 kDa subunit; signal peptidase complex subunit 1; SPase 12 kDa subunit
Orthologs:
Homo sapiens (human) : SPCS1 (signal peptidase complex subunit 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Spcs1 (signal peptidase complex subunit 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spcs1 (signal peptidase complex subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPCS1 (signal peptidase complex subunit 1)
Canis lupus familiaris (dog) : SPCS1 (signal peptidase complex subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spcs1 (signal peptidase complex subunit 1)
Sus scrofa (pig) : SPCS1 (signal peptidase complex subunit 1)
Chlorocebus sabaeus (African green monkey) : SPCS1 (signal peptidase complex subunit 1)
Heterocephalus glaber (naked mole-rat) : Spcs1 (signal peptidase complex subunit 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1430,999,826 - 31,001,672 (-)EnsemblGRCm38mm10GRCm38
GRCm381430,999,826 - 31,001,666 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371431,813,012 - 31,814,852 (-)NCBIGRCm37mm9NCBIm37
MGSCv361429,828,837 - 29,830,372 (-)NCBImm8
Celera1427,257,641 - 27,259,481 (-)NCBICelera
Cytogenetic Map14BNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Spcs1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550125
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.