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Gene: Spcs1 (signal peptidase complex subunit 1 homolog (S. cerevisiae)) Mus musculus
Symbol: Spcs1
Name: signal peptidase complex subunit 1 homolog (S. cerevisiae)
CRRD ID: 1550125
Description: Exhibits ribosome binding activity. Predicted to be involved in several processes, including protein targeting to ER; signal peptide processing; and viral protein processing. Predicted to localize to integral component of endoplasmic reticulum membrane and signal peptidase complex. Is expressed in several structures, including alimentary system; cranium; ear; integumental system; and nervous system. Orthologous to human SPCS1 (signal peptidase complex subunit 1); PARTICIPATES IN biotin metabolic pathway; biotinidase deficiency pathway; holocarboxylase synthetase deficiency pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810004F21Rik; microsomal signal peptidase 12 kDa subunit; signal peptidase complex subunit 1; SPase 12 kDa subunit
Homo sapiens (human) : SPCS1 (signal peptidase complex subunit 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Spcs1 (signal peptidase complex subunit 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spcs1 (signal peptidase complex subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPCS1 (signal peptidase complex subunit 1)
Canis lupus familiaris (dog) : SPCS1 (signal peptidase complex subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spcs1 (signal peptidase complex subunit 1)
Sus scrofa (pig) : SPCS1 (signal peptidase complex subunit 1)
Chlorocebus sabaeus (African green monkey) : SPCS1 (signal peptidase complex subunit 1)
Heterocephalus glaber (naked mole-rat) : Spcs1 (signal peptidase complex subunit 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1430,999,826 - 31,001,672 (-)EnsemblGRCm38mm10GRCm38
GRCm381430,999,826 - 31,001,666 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371431,813,012 - 31,814,852 (-)NCBIGRCm37mm9NCBIm37
MGSCv361429,828,837 - 29,830,372 (-)NCBImm8
Celera1427,257,641 - 27,259,481 (-)NCBICelera
Cytogenetic Map14BNCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Spcs1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550125
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.