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Gene: Acvr2a (activin receptor IIA) Mus musculus
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Symbol: Acvr2a
Name: activin receptor IIA
Description: Exhibits several functions, including BMP receptor activity; PDZ domain binding activity; and activin binding activity. Involved in several processes, including Sertoli cell proliferation; copulation; and regulation of nitric-oxide synthase activity. Localizes to the cell surface. Used to study Weissenbacher-Zweymuller syndrome. Human ortholog(s) of this gene implicated in colon cancer. Is expressed in several structures, including central nervous system; early conceptus; gonad; gut; and sensory organ. Orthologous to human ACVR2A (activin A receptor type 2A); PARTICIPATES IN activin signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; pirinixic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activin receptor type IIA; activin receptor type-2A; ACTR-IIA; ActrIIa; Acvr2; TactrII
Orthologs:
Homo sapiens (human) : ACVR2A (activin A receptor type 2A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acvr2a (activin A receptor type 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acvr2a (activin A receptor type 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVR2A (activin A receptor type 2A)
Canis lupus familiaris (dog) : ACVR2A (activin A receptor type 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvr2a (activin A receptor type 2A)
Sus scrofa (pig) : ACVR2A (activin A receptor type 2A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl248,814,109 - 48,903,269 (+)Ensembl
GRCm38248,814,109 - 48,903,264 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37248,669,629 - 48,758,784 (+)NCBIGRCm37mm9NCBIm37
MGSCv36248,636,166 - 48,724,172 (+)NCBImm8
Celera250,486,791 - 50,575,736 (+)NCBICelera
Cytogenetic Map2 C1.1NCBI
cM Map228.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Acvr2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550139
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.