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Gene: Acvr2a (activin receptor IIA) Mus musculus
Symbol: Acvr2a
Name: activin receptor IIA
Description: Exhibits several functions, including BMP receptor activity; PDZ domain binding activity; and activin binding activity. Involved in several processes, including Sertoli cell proliferation; copulation; and regulation of nitric-oxide synthase activity. Localizes to the cell surface. Used to study Weissenbacher-Zweymuller syndrome. Human ortholog(s) of this gene implicated in colon cancer. Is expressed in several structures, including central nervous system; early conceptus; gonad; gut; and sensory organ. Orthologous to human ACVR2A (activin A receptor type 2A); PARTICIPATES IN activin signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; pirinixic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activin receptor type IIA; activin receptor type-2A; ACTR-IIA; ActrIIa; Acvr2; TactrII
Homo sapiens (human) : ACVR2A (activin A receptor type 2A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acvr2a (activin A receptor type 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acvr2a (activin A receptor type 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVR2A (activin A receptor type 2A)
Canis lupus familiaris (dog) : ACVR2A (activin A receptor type 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvr2a (activin A receptor type 2A)
Sus scrofa (pig) : ACVR2A (activin A receptor type 2A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl248,814,109 - 48,903,269 (+)Ensembl
GRCm38248,814,109 - 48,903,264 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37248,669,629 - 48,758,784 (+)NCBIGRCm37mm9NCBIm37
MGSCv36248,636,166 - 48,724,172 (+)NCBImm8
Celera250,486,791 - 50,575,736 (+)NCBICelera
Cytogenetic Map2 C1.1NCBI
cM Map228.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Acvr2a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550139
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.