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Gene: Tnfrsf12a (tumor necrosis factor receptor superfamily, member 12a) Mus musculus
Symbol: Tnfrsf12a
Name: tumor necrosis factor receptor superfamily, member 12a
CRRD ID: 1550230
Description: Involved in several processes, including extrinsic apoptotic signaling pathway; positive regulation of axon extension; and substrate-dependent cell migration, cell attachment to substrate. Localizes to cell surface; plasma membrane; and ruffle. Is expressed in several structures, including adrenal medulla; genitourinary system; heart; limb long bone; and molar. Orthologous to human TNFRSF12A (TNF receptor superfamily member 12A); INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI255180; C87282; FGF-inducible 14; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; fibroblast growth factor-regulated protein 2; Fn1; Fn14; HPIP; tumor necrosis factor receptor superfamily member 12A; Twea; TWEAK; TWEAK-R; tweak-receptor; TweakR; type I transmembrane protein Fn14
Homo sapiens (human) : TNFRSF12A (TNF receptor superfamily member 12A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnfrsf12a (TNF receptor superfamily member 12A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfrsf12a (TNF receptor superfamily member 12A)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFRSF12A (TNF receptor superfamily member 12A)
Canis lupus familiaris (dog) : TNFRSF12A (TNF receptor superfamily member 12A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfrsf12a (TNF receptor superfamily member 12A)
Sus scrofa (pig) : TNFRSF12A (TNF receptor superfamily member 12A)
Chlorocebus sabaeus (African green monkey) : TNFRSF12A (TNF receptor superfamily member 12A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391723,894,419 - 23,896,423 (-)NCBI
GRCm381723,675,445 - 23,677,449 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,675,445 - 23,677,468 (-)EnsemblGRCm38mm10GRCm38
MGSCv371723,812,412 - 23,814,416 (-)NCBIGRCm37mm9NCBIm37
MGSCv361723,403,067 - 23,405,066 (-)NCBImm8
Celera1724,181,651 - 24,183,653 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tnfrsf12a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550230
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.