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Gene: Cd2ap (CD2-associated protein) Mus musculus
Symbol: Cd2ap
Name: CD2-associated protein
CRRD ID: 1550249
Description: Predicted to have several functions, including SH3 domain binding activity; beta-catenin binding activity; and protein C-terminus binding activity. Involved in negative regulation of transforming growth factor beta1 production; positive regulation of protein localization to nucleus; and regulation of actin cytoskeleton reorganization. Localizes to cell-cell junction; cytoplasm; and plasma membrane. Is expressed in several structures, including alimentary system; blastocyst; early embryo; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis. Orthologous to human CD2AP (CD2 associated protein).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AL024079; C78928; mesenchyme to epithelium transition protein, SH3 domains; mesenchyme-to-epithelium transition protein with SH3 domains 1; Mets; METS-; METS-1; Mets1; SH3 domain-containing adapter protein; SH3 domain-containing adaptor protein METS-1
Homo sapiens (human) : CD2AP (CD2 associated protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd2ap (CD2-associated protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd2ap (CD2 associated protein)
Pan paniscus (bonobo/pygmy chimpanzee) : CD2AP (CD2 associated protein)
Canis lupus familiaris (dog) : CD2AP (CD2 associated protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd2ap (CD2 associated protein)
Sus scrofa (pig) : CD2AP (CD2 associated protein)
Chlorocebus sabaeus (African green monkey) : CD2AP (CD2 associated protein)
Heterocephalus glaber (naked mole-rat) : Cd2ap (CD2 associated protein)
more info ...
Related Pseudogenes: Gm6475   Gm7529  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391743,059,857 - 43,187,595 (-)NCBI
GRCm381742,748,887 - 42,876,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1742,792,951 - 42,876,665 (-)EnsemblGRCm38mm10GRCm38
MGSCv371742,929,900 - 43,013,373 (-)NCBIGRCm37mm9NCBIm37
MGSCv361742,256,435 - 42,352,155 (-)NCBImm8
Celera1746,201,889 - 46,261,450 (-)NCBICelera
Cytogenetic Map17B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cd2ap
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550249
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.