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Gene: Sfrp2 (secreted frizzled-related protein 2) Mus musculus
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Symbol: Sfrp2
Name: secreted frizzled-related protein 2
CRRD ID: 1550582
Description: Exhibits Wnt-protein binding activity; endopeptidase activator activity; and receptor ligand activity. Involved in several processes, including animal organ development; negative regulation of signal transduction; and regulation of cellular protein metabolic process. Localizes to extracellular space. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; eye; and genitourinary system. Orthologous to human SFRP2 (secreted frizzled related protein 2); PARTICIPATES IN Wnt signaling, canonical pathway; Wnt signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI851596; SARP-1; Sdf; Sdf5; secreted apoptosis-related protein 1; secreted frizzled-related sequence protein 2; secreted frizzled-related sequence protein 5; sFRP-2; stromal cell derived factor 5
Orthologs:
Homo sapiens (human) : SFRP2 (secreted frizzled related protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sfrp2 (secreted frizzled-related protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sfrp2 (secreted frizzled related protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SFRP2 (secreted frizzled related protein 2)
Canis lupus familiaris (dog) : SFRP2 (secreted frizzled related protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sfrp2 (secreted frizzled related protein 2)
Sus scrofa (pig) : SFRP2 (secreted frizzled related protein 2)
Chlorocebus sabaeus (African green monkey) : SFRP2 (secreted frizzled related protein 2)
Heterocephalus glaber (naked mole-rat) : Sfrp2 (secreted frizzled related protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39383,673,628 - 83,681,621 (+)NCBI
GRCm38383,765,750 - 83,774,314 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl383,766,321 - 83,774,316 (+)EnsemblGRCm38mm10GRCm38
MGSCv37383,570,243 - 83,578,236 (+)NCBIGRCm37mm9NCBIm37
MGSCv36383,852,248 - 83,860,242 (+)NCBImm8
Celera383,778,926 - 83,786,923 (+)NCBICelera
Cytogenetic Map3E3NCBI
cM Map337.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sfrp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550582
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.