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Gene: Sfrp2 (secreted frizzled-related protein 2) Mus musculus
Symbol: Sfrp2
Name: secreted frizzled-related protein 2
CRRD ID: 1550582
Description: Exhibits Wnt-protein binding activity; endopeptidase activator activity; and receptor ligand activity. Involved in several processes, including animal organ development; negative regulation of signal transduction; and regulation of cellular protein metabolic process. Localizes to extracellular space. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; eye; and genitourinary system. Orthologous to human SFRP2 (secreted frizzled related protein 2); PARTICIPATES IN Wnt signaling, canonical pathway; Wnt signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI851596; SARP-1; Sdf; Sdf5; secreted apoptosis-related protein 1; secreted frizzled-related sequence protein 2; secreted frizzled-related sequence protein 5; sFRP-2; stromal cell derived factor 5
Homo sapiens (human) : SFRP2 (secreted frizzled related protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sfrp2 (secreted frizzled-related protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sfrp2 (secreted frizzled related protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SFRP2 (secreted frizzled related protein 2)
Canis lupus familiaris (dog) : SFRP2 (secreted frizzled related protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sfrp2 (secreted frizzled related protein 2)
Sus scrofa (pig) : SFRP2 (secreted frizzled related protein 2)
Chlorocebus sabaeus (African green monkey) : SFRP2 (secreted frizzled related protein 2)
Heterocephalus glaber (naked mole-rat) : Sfrp2 (secreted frizzled related protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39383,673,628 - 83,681,621 (+)NCBI
GRCm38383,765,750 - 83,774,314 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl383,766,321 - 83,774,316 (+)EnsemblGRCm38mm10GRCm38
MGSCv37383,570,243 - 83,578,236 (+)NCBIGRCm37mm9NCBIm37
MGSCv36383,852,248 - 83,860,242 (+)NCBImm8
Celera383,778,926 - 83,786,923 (+)NCBICelera
Cytogenetic Map3E3NCBI
cM Map337.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sfrp2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550582
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.