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Gene: Hdac4 (histone deacetylase 4) Mus musculus
Symbol: Hdac4
Name: histone deacetylase 4
Description: Exhibits several functions, including protein deacetylase activity; protein kinase binding activity; and transcription corepressor activity. Predicted to contribute to sequence-specific DNA binding activity and transcription regulatory region DNA binding activity. Involved in several processes, including osteoblast development; regulation of muscle system process; and regulation of nucleobase-containing compound metabolic process. Localizes to several cellular components, including the actomyosin; cytosol; and neuromuscular junction. Human ortholog(s) of this gene implicated in ataxia telangiectasia; eating disorder; and retinal degeneration. Is expressed in alimentary system; early embryo; ganglia; hand; and vibrissa. Orthologous to human HDAC4 (histone deacetylase 4); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4932408F19Rik; AI047285; HD4
Homo sapiens (human) : HDAC4 (histone deacetylase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hdac4 (histone deacetylase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac4 (histone deacetylase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC4 (histone deacetylase 4)
Canis lupus familiaris (dog) : HDAC4 (histone deacetylase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac4 (histone deacetylase 4)
Sus scrofa (pig) : HDAC4 (histone deacetylase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl191,928,779 - 92,195,699 (-)Ensembl
GRCm38191,928,779 - 92,195,702 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37193,829,311 - 94,044,970 (-)NCBIGRCm37mm9NCBIm37
MGSCv36193,763,140 - 93,978,799 (-)NCBImm8
Celera194,870,648 - 95,086,759 (-)NCBICelera
Cytogenetic Map1 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hdac4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550759
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.