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Gene: Hdac4 (histone deacetylase 4) Mus musculus
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Symbol: Hdac4
Name: histone deacetylase 4
Description: Exhibits several functions, including protein deacetylase activity; protein kinase binding activity; and transcription corepressor activity. Predicted to contribute to sequence-specific DNA binding activity and transcription regulatory region DNA binding activity. Involved in several processes, including osteoblast development; regulation of muscle system process; and regulation of nucleobase-containing compound metabolic process. Localizes to several cellular components, including the actomyosin; cytosol; and neuromuscular junction. Human ortholog(s) of this gene implicated in ataxia telangiectasia; eating disorder; and retinal degeneration. Is expressed in alimentary system; early embryo; ganglia; hand; and vibrissa. Orthologous to human HDAC4 (histone deacetylase 4); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4932408F19Rik; AI047285; HD4
Orthologs:
Homo sapiens (human) : HDAC4 (histone deacetylase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hdac4 (histone deacetylase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac4 (histone deacetylase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC4 (histone deacetylase 4)
Canis lupus familiaris (dog) : HDAC4 (histone deacetylase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac4 (histone deacetylase 4)
Sus scrofa (pig) : HDAC4 (histone deacetylase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl191,928,779 - 92,195,699 (-)Ensembl
GRCm38191,928,779 - 92,195,702 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37193,829,311 - 94,044,970 (-)NCBIGRCm37mm9NCBIm37
MGSCv36193,763,140 - 93,978,799 (-)NCBImm8
Celera194,870,648 - 95,086,759 (-)NCBICelera
Cytogenetic Map1 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hdac4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550759
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.