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Gene: Lgr5 (leucine rich repeat containing G protein coupled receptor 5) Mus musculus
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Symbol: Lgr5
Name: leucine rich repeat containing G protein coupled receptor 5
Description: Exhibits transmembrane signaling receptor activity. Involved in several processes, including epithelial cell proliferation involved in renal tubule morphogenesis; hair follicle development; and positive regulation of canonical Wnt signaling pathway. Predicted to localize to the integral component of plasma membrane and trans-Golgi network membrane. Used to study ankyloglossia. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; reproductive system; and sensory organ. Orthologous to human LGR5 (leucine rich repeat containing G protein-coupled receptor 5).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FEX; follicle expressed hormone; G protein-coupled receptor 49; G-protein coupled receptor 49; Gpr49; leucine-rich repeat-containing G-protein coupled receptor 5; orphan G-protein coupled receptor FEX
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3810115,450,314 - 115,587,780 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710114,887,370 - 115,024,836 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610114,855,736 - 114,991,603 (-)NCBImm8
Celera10117,380,191 - 117,518,061 (-)NCBICelera
Cytogenetic Map10 D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lgr5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550798
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.