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Gene: Prepl (prolyl endopeptidase-like) Mus musculus
Symbol: Prepl
Name: prolyl endopeptidase-like
Description: Exhibits peptidase activity. Involved in Golgi to plasma membrane protein transport and retrograde transport, endosome to Golgi. Localizes to Golgi apparatus and cytoskeleton. Colocalizes with trans-Golgi network. Is expressed in several structures, including diaphragm; nervous system; retina; tongue; and vertebral axis musculature. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 22. Orthologous to human PREPL (prolyl endopeptidase like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; cyclosporin A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810457N15Rik; 9530014L06Rik; D030028O16Rik; MGC7980; mKIAA0436
Homo sapiens (human) : PREPL (prolyl endopeptidase like)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prepl (prolyl endopeptidase-like)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prepl (prolyl endopeptidase like)
Pan paniscus (bonobo/pygmy chimpanzee) : PREPL (prolyl endopeptidase like)
Canis lupus familiaris (dog) : PREPL (prolyl endopeptidase like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prepl (prolyl endopeptidase like)
Sus scrofa (pig) : PREPL (prolyl endopeptidase like)
Chlorocebus sabaeus (African green monkey) : PREPL (prolyl endopeptidase like)
Heterocephalus glaber (naked mole-rat) : Prepl (prolyl endopeptidase like)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1785,063,470 - 85,090,241 (-)EnsemblGRCm38mm10GRCm38
GRCm381785,062,511 - 85,090,504 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371785,462,817 - 85,489,614 (-)NCBIGRCm37mm9NCBIm37
MGSCv361784,971,812 - 84,998,534 (-)NCBImm8
Celera1789,425,166 - 89,451,900 (-)NCBICelera
Cytogenetic Map17E4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Prepl
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550884
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.