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Gene: Phlpp1 (PH domain and leucine rich repeat protein phosphatase 1) Mus musculus
Symbol: Phlpp1
Name: PH domain and leucine rich repeat protein phosphatase 1
CRRD ID: 1550945
Description: Predicted to have protein serine/threonine phosphatase activity. Involved in entrainment of circadian clock and regulation of T cell anergy. Predicted to localize to cytoplasm; nucleus; and plasma membrane. Is expressed in ventricular layer. Orthologous to human PHLPP1 (PH domain and leucine rich repeat protein phosphatase 1); PARTICIPATES IN phosphatidylinositol 3-kinase-Akt signaling pathway; protein kinase C (PKC) signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI836256; mKIAA0606; P; PH domain leucine-rich repeat-containing protein phosphatase 1; PH domain-containing family E member 1; Phlpp; pleckstrin homology domain containing, family E (with leucine rich repeats) member 1; pleckstrin homology domain-containing family E member 1; Plekh; Plekhe1; SCOP; suprachiasmatic nucleus circadian oscillatory protein
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391106,099,599 - 106,321,975 (+)NCBI
GRCm381106,171,869 - 106,394,245 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1106,171,752 - 106,394,250 (+)EnsemblGRCm38mm10GRCm38
MGSCv371108,068,446 - 108,290,822 (+)NCBIGRCm37mm9NCBIm37
MGSCv361107,999,416 - 108,221,797 (+)NCBImm8
Celera1109,020,809 - 109,235,924 (+)NCBICelera
Cytogenetic Map1E2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Phlpp1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550945
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.