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Gene: Ptpa (protein phosphatase 2 protein activator) Mus musculus
Symbol: Ptpa
Name: protein phosphatase 2 protein activator
Description: Predicted to contribute to ATPase activity. Predicted to be involved in mitotic spindle organization; positive regulation of apoptotic process; and regulation of phosphoprotein phosphatase activity. Predicted to localize to several cellular components, including the calcium channel complex; nucleoplasm; and protein phosphatase type 2A complex. Is expressed in embryo and forelimb bud. Orthologous to human PTPA (protein phosphatase 2 phosphatase activator); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610042B21Rik; C77440; MGC60706; MGC7129; N28142; phosphotyrosyl phosphatase activator; PP2A, subunit B', PR53 isoform; Ppp2r4; PR53; protein phosphatase 2A, regulatory subunit B (PR 53); serine/threonine-protein phosphatase 2A activator; serine/threonine-protein phosphatase 2A regulatory subunit 4; serine/threonine-protein phosphatase 2A regulatory subunit B'
Homo sapiens (human) : PTPA (protein phosphatase 2 phosphatase activator)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptpa (protein phosphatase 2 phosphatase activator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptpa (protein phosphatase 2 phosphatase activator)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPA (protein phosphatase 2 phosphatase activator)
Canis lupus familiaris (dog) : PTPA (protein phosphatase 2 phosphatase activator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptpa (protein phosphatase 2 phosphatase activator)
Sus scrofa (pig) : PTPA (protein phosphatase 2 phosphatase activator)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38230,416,050 - 30,447,807 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37230,271,570 - 30,303,327 (+)NCBIGRCm37mm9NCBIm37
MGSCv36230,238,059 - 30,269,813 (+)NCBImm8
Celera230,120,848 - 30,152,502 (+)NCBICelera
Cytogenetic Map2 BNCBI
cM Map221.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ptpa
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1550971
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.