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Gene: Myd88 (myeloid differentiation primary response gene 88) Mus musculus
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Symbol: Myd88
Name: myeloid differentiation primary response gene 88
Description: Exhibits Toll-like receptor binding activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of intracellular signal transduction; and response to bacterium. Localizes to the cytosol and plasma membrane. Human ortholog(s) of this gene implicated in Waldenstroem's macroglobulinemia. Is expressed in cerebral cortex and telencephalon. Orthologous to human MYD88 (MYD88 innate immune signal transduction adaptor); PARTICIPATES IN interleukin-1 signaling pathway; Toll-like receptor signaling pathway; apoptotic cell death pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: myeloid differentiation primary response protein 88; myeloid differentiation primary response protein MyD88
Orthologs:
Homo sapiens (human) : MYD88 (MYD88 innate immune signal transduction adaptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myd88 (MYD88, innate immune signal transduction adaptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myd88 (MYD88 innate immune signal transduction adaptor)
Pan paniscus (bonobo/pygmy chimpanzee) : MYD88 (MYD88 innate immune signal transduction adaptor)
Canis lupus familiaris (dog) : MYD88 (MYD88 innate immune signal transduction adaptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myd88 (MYD88 innate immune signal transduction adaptor)
Sus scrofa (pig) : MYD88 (MYD88 innate immune signal transduction adaptor)
Chlorocebus sabaeus (green monkey) : MYD88 (MYD88 innate immune signal transduction adaptor)
Heterocephalus glaber (naked mole-rat) : Myd88 (MYD88 innate immune signal transduction adaptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl9119,335,934 - 119,341,411 (-)Ensembl
GRCm389119,335,934 - 119,340,018 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379119,245,106 - 119,249,158 (-)NCBIGRCm37mm9NCBIm37
MGSCv369119,184,686 - 119,188,738 (-)NCBImm8
Celera9119,805,118 - 119,809,170 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map971.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Myd88
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551097
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.