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Gene: Nprl3 (nitrogen permease regulator-like 3) Mus musculus
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Symbol: Nprl3
Name: nitrogen permease regulator-like 3
Description: Predicted to contribute to GTPase activator activity. Involved in circulatory system development and roof of mouth development. Predicted to localize to GATOR1 complex and lysosomal membrane. Human ortholog(s) of this gene implicated in focal epilepsy. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human NPRL3 (NPR3 like, GATOR1 complex subunit); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; arsane (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: -14; Aag; alpha globin regulatory element containing; alpha-globin regulatory element-containing gene protein; CGTHBA; GATOR complex protein NPRL3; HS-26; HS-40; m(alpha)RE; Mare; nitrogen permease regulator 3-like protein; Phg; Prox1; proximal locus to the hemoglobin alpha chain complex
Orthologs:
Homo sapiens (human) : NPRL3 (NPR3 like, GATOR1 complex subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nprl3 (NPR3-like, GATOR1 complex subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nprl3 (NPR3 like, GATOR1 complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Canis lupus familiaris (dog) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nprl3 (NPR3 like, GATOR1 complex subunit)
Sus scrofa (pig) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Chlorocebus sabaeus (African green monkey) : NPRL3 (NPR3 like, GATOR1 complex subunit)
Heterocephalus glaber (naked mole-rat) : Nprl3 (NPR3 like, GATOR1 complex subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1132,225,628 - 32,267,707 (-)EnsemblGRCm38mm10GRCm38
GRCm381132,231,963 - 32,267,707 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371132,132,419 - 32,167,614 (-)NCBIGRCm37mm9NCBIm37
MGSCv361132,132,419 - 32,167,614 (-)NCBImm8
Celera1134,649,697 - 34,684,772 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Nprl3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551104
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.