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Gene: Gna11 (guanine nucleotide binding protein, alpha 11) Mus musculus
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Symbol: Gna11
Name: guanine nucleotide binding protein, alpha 11
Description: Predicted to have several functions, including G-protein beta/gamma-subunit complex binding activity; GTP binding activity; and alkylglycerophosphoethanolamine phosphodiesterase activity. Involved in several processes, including cellular response to pH; phospholipase C-activating dopamine receptor signaling pathway; and regulation of melanocyte differentiation. Predicted to localize to the cytosol and heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in autosomal dominant hypocalcemia 2 and familial hypocalciuric hypercalcemia 2. Is expressed in brain; early conceptus; genitourinary system; heart; and tooth. Orthologous to human GNA11 (G protein subunit alpha 11); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; angiotensin II signaling pathway via AT1 receptor; eicosanoid signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Dsk7; E430025L19; g alpha-11; G-protein subunit alpha-11; guanine nucleotide-binding protein subunit alpha-11
Orthologs:
Homo sapiens (human) : GNA11 (G protein subunit alpha 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gna11 (G protein subunit alpha 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gna11 (G protein subunit alpha 11)
Pan paniscus (bonobo/pygmy chimpanzee) : GNA11 (G protein subunit alpha 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gna11 (G protein subunit alpha 11)
Sus scrofa (pig) : GNA11 (G protein subunit alpha 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1081,528,724 - 81,545,190 (-)Ensembl
GRCm381081,528,724 - 81,545,162 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371080,991,477 - 81,007,791 (-)NCBIGRCm37mm9NCBIm37
MGSCv361080,931,861 - 80,948,175 (-)NCBImm8
Celera1082,551,913 - 82,568,227 (-)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gna11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551128
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.