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Gene: Gna11 (guanine nucleotide binding protein, alpha 11) Mus musculus
Symbol: Gna11
Name: guanine nucleotide binding protein, alpha 11
Description: Predicted to have several functions, including G-protein beta/gamma-subunit complex binding activity; GTP binding activity; and alkylglycerophosphoethanolamine phosphodiesterase activity. Involved in several processes, including cellular response to pH; phospholipase C-activating dopamine receptor signaling pathway; and regulation of melanocyte differentiation. Predicted to localize to the cytosol and heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in autosomal dominant hypocalcemia 2 and familial hypocalciuric hypercalcemia 2. Is expressed in brain; early conceptus; genitourinary system; heart; and tooth. Orthologous to human GNA11 (G protein subunit alpha 11); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; angiotensin II signaling pathway via AT1 receptor; eicosanoid signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Dsk7; E430025L19; g alpha-11; G-protein subunit alpha-11; guanine nucleotide-binding protein subunit alpha-11
Homo sapiens (human) : GNA11 (G protein subunit alpha 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gna11 (G protein subunit alpha 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gna11 (G protein subunit alpha 11)
Pan paniscus (bonobo/pygmy chimpanzee) : GNA11 (G protein subunit alpha 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gna11 (G protein subunit alpha 11)
Sus scrofa (pig) : GNA11 (G protein subunit alpha 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1081,528,724 - 81,545,190 (-)Ensembl
GRCm381081,528,724 - 81,545,162 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371080,991,477 - 81,007,791 (-)NCBIGRCm37mm9NCBIm37
MGSCv361080,931,861 - 80,948,175 (-)NCBImm8
Celera1082,551,913 - 82,568,227 (-)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gna11
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551128
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.