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Gene: Nsd3 (nuclear receptor binding SET domain protein 3) Mus musculus
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Symbol: Nsd3
Name: nuclear receptor binding SET domain protein 3
CRRD ID: 1551135
Description: Exhibits histone methyltransferase activity (H3-K27 specific) and histone methyltransferase activity (H3-K4 specific). Involved in negative regulation of transcription, DNA-templated. Predicted to localize to chromatin and nucleus. Is expressed in metanephros and renal vasculature. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human NSD3 (nuclear receptor binding SET domain protein 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6720429E03; A530023P05; AI528490; histone-lysine N-methyltransferase NSD3; nuclear SET domain-containing protein 3; WHIS; WHISTLE; Whsc1; WHSC1-like protein 1; Whsc1l1; Wolf-Hirschhorn syndrome candidate 1-like 1 (human); wolf-Hirschhorn syndrome candidate 1-like protein 1 homolog
Orthologs:
Homo sapiens (human) : NSD3 (nuclear receptor binding SET domain protein 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nsd3 (nuclear receptor binding SET domain protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nsd3 (nuclear receptor binding SET domain protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NSD3 (nuclear receptor binding SET domain protein 3)
Canis lupus familiaris (dog) : NSD3 (nuclear receptor binding SET domain protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nsd3 (nuclear receptor binding SET domain protein 3)
Sus scrofa (pig) : NSD3 (nuclear receptor binding SET domain protein 3)
Chlorocebus sabaeus (African green monkey) : NSD3 (nuclear receptor binding SET domain protein 3)
Heterocephalus glaber (naked mole-rat) : Nsd3 (nuclear receptor binding SET domain protein 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39826,091,617 - 26,209,694 (+)NCBI
GRCm38825,601,601 - 25,719,667 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl825,601,601 - 25,719,667 (+)EnsemblGRCm38mm10GRCm38
MGSCv37826,712,778 - 26,830,139 (+)NCBIGRCm37mm9NCBIm37
MGSCv36827,067,146 - 27,185,212 (+)NCBImm8
Celera827,070,741 - 27,187,953 (+)NCBICelera
Cytogenetic Map8A2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Nsd3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551135
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.