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Gene: Marchf7 (membrane associated ring-CH-type finger 7) Mus musculus
Symbol: Marchf7
Name: membrane associated ring-CH-type finger 7
CRRD ID: 1551140
Description: Exhibits enzyme binding activity and ubiquitin binding activity. Involved in negative regulation of T cell proliferation; protein autoubiquitination; and regulation of tolerance induction. Localizes to cytosol; nucleus; and plasma membrane. Is expressed in brain; early conceptus; and telencephalon. Orthologous to human MARCHF7 (membrane associated ring-CH-type finger 7); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 4,4'-diaminodiphenylmethane.
Type: protein-coding
Also known as: Ax; Axo; Axot; axotrophin; E3 ubiquitin-protein ligase MARCH7; E3 ubiquitin-protein ligase MARCHF7; gene trap ROSA b-geo 17; Gtrgeo; Gtrgeo17; Marc; MARCH-VII; March7; membrane-associated ring finger (C3HC4) 7; membrane-associated RING finger protein 7; membrane-associated RING-CH protein VII; RING-type E3 ubiquitin transferase MARCH7; RING-type E3 ubiquitin transferase MARCHF7
Homo sapiens (human) : MARCHF7 (membrane associated ring-CH-type finger 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Marchf7 (membrane associated ring-CH-type finger 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Marchf7 (membrane associated ring-CH-type finger 7)
Pan paniscus (bonobo/pygmy chimpanzee) : MARCHF7 (membrane associated ring-CH-type finger 7)
Canis lupus familiaris (dog) : MARCHF7 (membrane associated ring-CH-type finger 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Marchf7 (membrane associated ring-CH-type finger 7)
Sus scrofa (pig) : MARCHF7 (membrane associated ring-CH-type finger 7)
Chlorocebus sabaeus (African green monkey) : MARCHF7 (membrane associated ring-CH-type finger 7)
Heterocephalus glaber (naked mole-rat) : Marchf7 (membrane associated ring-CH-type finger 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl260,209,887 - 60,250,676 (+)EnsemblGRCm38mm10GRCm38
GRCm38260,209,936 - 60,248,385 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37260,047,993 - 60,086,442 (+)NCBIGRCm37mm9NCBIm37
MGSCv36260,010,775 - 60,049,224 (+)NCBImm8
Celera261,923,924 - 61,943,391 (+)NCBICelera
Cytogenetic Map2C1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Marchf7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551140
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.