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Gene: Marchf8 (membrane associated ring-CH-type finger 8) Mus musculus
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Symbol: Marchf8
Name: membrane associated ring-CH-type finger 8
CRRD ID: 1551233
Description: Exhibits MHC class II protein binding activity and ubiquitin protein ligase activity. Involved in antigen processing and presentation of peptide antigen via MHC class II; negative regulation of MHC class II biosynthetic process; and protein ubiquitination. Predicted to localize to early endosome membrane; late endosome membrane; and lysosome. Orthologous to human MARCHF8 (membrane associated ring-CH-type finger 8).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1300017E09Rik; c-mir, cellular modulator of immune recognition; cellular modulator of immune recognition; E3 ubiquitin-protein ligase MARCH8; E3 ubiquitin-protein ligase MARCHF8; M; Marc; MARCH-VIII; March8; membrane-associated ring finger (C3HC4) 8; membrane-associated RING finger protein 8; membrane-associated RING-CH protein VIII; Mir; RING-type E3 ubiquitin transferase MARCH8; RING-type E3 ubiquitin transferase MARCHF8
Orthologs:
Homo sapiens (human) : MARCHF8 (membrane associated ring-CH-type finger 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Marchf8 (membrane associated ring-CH-type finger 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Marchf8 (membrane associated ring-CH-type finger 8)
Pan paniscus (bonobo/pygmy chimpanzee) : MARCHF8 (membrane associated ring-CH-type finger 8)
Canis lupus familiaris (dog) : MARCHF8 (membrane associated ring-CH-type finger 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Marchf8 (membrane associated ring-CH-type finger 8)
Sus scrofa (pig) : MARCHF8 (membrane associated ring-CH-type finger 8)
Chlorocebus sabaeus (African green monkey) : MARCHF8 (membrane associated ring-CH-type finger 8)
Heterocephalus glaber (naked mole-rat) : Marchf8 (membrane associated ring-CH-type finger 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396116,312,546 - 116,386,501 (+)NCBI
GRCm386116,337,599 - 116,409,540 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6116,338,024 - 116,409,540 (+)EnsemblGRCm38mm10GRCm38
MGSCv376116,288,141 - 116,359,558 (+)NCBIGRCm37mm9NCBIm37
MGSCv366116,303,742 - 116,375,159 (+)NCBImm8
Celera6118,176,248 - 118,247,139 (+)NCBICelera
Cytogenetic Map6E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Marchf8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551233
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.