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Gene: Csf2 (colony stimulating factor 2 (granulocyte-macrophage)) Mus musculus
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Symbol: Csf2
Name: colony stimulating factor 2 (granulocyte-macrophage)
Description: Exhibits cytokine activity. Involved in several processes, including embryonic placenta development; myeloid leukocyte differentiation; and positive regulation of cell population proliferation. Localizes to the extracellular space. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Is expressed in several structures, including genitourinary system; hemolymphoid system; labyrinthine zone; liver; and lung. Orthologous to human CSF2 (colony stimulating factor 2); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; syndecan signaling pathway; INTERACTS WITH 1,4-benzoquinone; 1,4-phenylenediamine; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: colony-stimulating factor; CSF; Csfgm; Gm-CSf; GMCSF; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC151255; MGC151257; MGI-IGM; put. GM-CSF
Orthologs:
Homo sapiens (human) : CSF2 (colony stimulating factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Csf2 (colony stimulating factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf2 (colony stimulating factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF2 (colony stimulating factor 2)
Canis lupus familiaris (dog) : CSF2 (colony stimulating factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf2 (colony stimulating factor 2)
Sus scrofa (pig) : CSF2 (colony stimulating factor 2)
Chlorocebus sabaeus (green monkey) : CSF2 (colony stimulating factor 2)
Heterocephalus glaber (naked mole-rat) : Csf2 (colony stimulating factor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1154,247,271 - 54,249,667 (-)Ensembl
GRCm381154,247,270 - 54,249,899 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371154,060,772 - 54,063,401 (-)NCBIGRCm37mm9NCBIm37
MGSCv361154,090,687 - 54,093,065 (-)NCBImm8
Celera1158,835,805 - 58,838,455 (-)NCBICelera
Cytogenetic Map11 B1.3NCBI
cM Map1132.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Csf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551314
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.