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Gene: Abhd5 (abhydrolase domain containing 5) Mus musculus
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Symbol: Abhd5
Name: abhydrolase domain containing 5
Description: Predicted to have 1-acylglycerol-3-phosphate O-acyltransferase activity and carboxylic ester hydrolase activity. Involved in negative regulation of sequestering of triglyceride; positive regulation of lipoprotein lipase activity; and positive regulation of triglyceride catabolic process. Localizes to cytosol and lipid droplet. Used to study neutral lipid storage disease. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1 and neutral lipid storage disease. Is expressed in central nervous system; dorsal root ganglion; and retina. Orthologous to human ABHD5 (abhydrolase domain containing 5, lysophosphatidic acid acyltransferase); INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-acylglycerol-3-phosphate O-acyltransferase ABHD5; 1300003D03Rik; 2010002J10Rik; abhydrolase domain-containing protein 5; CDS; CGI-58; IECN5; lipid droplet-binding protein CGI-58; NCIE2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl9122,351,608 - 122,381,524 (+)EnsemblGRCm38mm10GRCm38
GRCm389122,351,616 - 122,381,524 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379122,260,734 - 122,290,641 (+)NCBIGRCm37mm9NCBIm37
MGSCv369122,200,314 - 122,230,221 (+)NCBImm8
Celera9122,816,005 - 122,845,910 (+)NCBICelera
Cytogenetic Map9F4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Abhd5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551382
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.