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Gene: Ambra1 (autophagy/beclin 1 regulator 1) Mus musculus
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Symbol: Ambra1
Name: autophagy/beclin 1 regulator 1
Description: Predicted to have GTPase binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including autophagy; negative regulation of neuron apoptotic process; and neural tube development. Localizes to the axoneme; cytosol; and phagocytic vesicle. Predicted to colocalize with the mitochondrion. Is expressed in main olfactory bulb. Orthologous to human AMBRA1 (autophagy and beclin 1 regulator 1); PARTICIPATES IN inositol metabolic pathway; mitochondrial autophagy pathway; phosphoinositide metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; phenobarbital.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310079H06Rik; A130023A14; AA474864; activating molecule in Beclin1-regulated autophagy; activating molecule in BECN1-regulated autophagy protein 1; AV021921; D030051N19Rik; mKIAA1736; RP23-273F8.1
Orthologs:
Homo sapiens (human) : AMBRA1 (autophagy and beclin 1 regulator 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ambra1 (autophagy and beclin 1 regulator 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ambra1 (autophagy and beclin 1 regulator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AMBRA1 (autophagy and beclin 1 regulator 1)
Canis lupus familiaris (dog) : AMBRA1 (autophagy and beclin 1 regulator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ambra1 (autophagy and beclin 1 regulator 1)
Sus scrofa (pig) : AMBRA1 (autophagy and beclin 1 regulator 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38291,730,138 - 91,918,849 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37291,570,295 - 91,759,006 (+)NCBIGRCm37mm9NCBIm37
MGSCv36291,531,062 - 91,719,688 (+)NCBImm8
Celera293,119,370 - 93,309,250 (+)NCBICelera
Cytogenetic Map2 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ambra1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551408
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.