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Gene: Ambra1 (autophagy/beclin 1 regulator 1) Mus musculus
Symbol: Ambra1
Name: autophagy/beclin 1 regulator 1
Description: Predicted to have GTPase binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including autophagy; negative regulation of neuron apoptotic process; and neural tube development. Localizes to the axoneme; cytosol; and phagocytic vesicle. Predicted to colocalize with the mitochondrion. Is expressed in main olfactory bulb. Orthologous to human AMBRA1 (autophagy and beclin 1 regulator 1); PARTICIPATES IN inositol metabolic pathway; mitochondrial autophagy pathway; phosphoinositide metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; phenobarbital.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310079H06Rik; A130023A14; AA474864; activating molecule in Beclin1-regulated autophagy; activating molecule in BECN1-regulated autophagy protein 1; AV021921; D030051N19Rik; mKIAA1736; RP23-273F8.1
Homo sapiens (human) : AMBRA1 (autophagy and beclin 1 regulator 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ambra1 (autophagy and beclin 1 regulator 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ambra1 (autophagy and beclin 1 regulator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AMBRA1 (autophagy and beclin 1 regulator 1)
Canis lupus familiaris (dog) : AMBRA1 (autophagy and beclin 1 regulator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ambra1 (autophagy and beclin 1 regulator 1)
Sus scrofa (pig) : AMBRA1 (autophagy and beclin 1 regulator 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38291,730,138 - 91,918,849 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37291,570,295 - 91,759,006 (+)NCBIGRCm37mm9NCBIm37
MGSCv36291,531,062 - 91,719,688 (+)NCBImm8
Celera293,119,370 - 93,309,250 (+)NCBICelera
Cytogenetic Map2 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ambra1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551408
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.