Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Sptbn1 (spectrin beta, non-erythrocytic 1) Mus musculus
Symbol: Sptbn1
Name: spectrin beta, non-erythrocytic 1
Description: Predicted to have GTPase binding activity and ankyrin binding activity. Involved in common-partner SMAD protein phosphorylation; protein localization to plasma membrane; and regulation of SMAD protein signal transduction. Localizes to several cellular components, including the M band; axolemma; and cuticular plate. Used to study Beckwith-Wiedemann syndrome. Is expressed in several structures, including brain; liver; sciatic nerve; spinal cord; and spleen. Orthologous to human SPTBN1 (spectrin beta, non-erythrocytic 1); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9930031C03Rik; AL033301; beta fodrin; beta-II spectrin; beta-spectrin 2, non-erythrocytic; brain spectrin; elf1; elf3; embryonic liver fodrin; fodrin beta chain; KIAA4049; mKIAA4049; non-erythrocytic; spectrin beta 2; spectrin beta chain, brain 1; spectrin beta chain, non-erythrocytic 1; spectrin G; spectrin, non-erythroid beta chain 1; Spnb-2; Spnb2; SPTB2
Homo sapiens (human) : SPTBN1 (spectrin beta, non-erythrocytic 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sptbn1 (spectrin, beta, non-erythrocytic 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sptbn1 (spectrin beta, non-erythrocytic 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPTBN1 (spectrin beta, non-erythrocytic 1)
Canis lupus familiaris (dog) : SPTBN1 (spectrin beta, non-erythrocytic 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sptbn1 (spectrin beta, non-erythrocytic 1)
Sus scrofa (pig) : SPTBN1 (spectrin beta, non-erythrocytic 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1130,099,395 - 30,268,175 (-)Ensembl
GRCm381130,099,395 - 30,268,384 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371129,999,395 - 30,119,772 (-)NCBIGRCm37mm9NCBIm37
MGSCv361130,000,434 - 30,119,772 (-)NCBImm8
Celera1132,468,358 - 32,593,393 (-)NCBICelera
Cytogenetic Map11 A3.3NCBI
cM Map1117.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Sptbn1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551425
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.