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Gene: Zhx2 (zinc fingers and homeoboxes 2) Mus musculus
Symbol: Zhx2
Name: zinc fingers and homeoboxes 2
Description: Predicted to have DNA-binding transcription factor activity; protein dimerization activity; and transcription corepressor activity. Involved in generation of neurons; negative regulation of gene expression; and somatic stem cell population maintenance. Localizes to the nucleus. Is expressed in brain; liver; and renal vasculature. Orthologous to human ZHX2 (zinc fingers and homeoboxes 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AFP regulator 1; Afr-1; Afr1; alpha fetoprotein regulation 1, adult; alpha-fetoprotein regulator 1; mKIAA0854; Raf; regulator of AFP; zinc finger and homeodomain protein 2; zinc fingers and homeoboxes protein 2
Homo sapiens (human) : ZHX2 (zinc fingers and homeoboxes 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Zhx2 (zinc fingers and homeoboxes 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zhx2 (zinc fingers and homeoboxes 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ZHX2 (zinc fingers and homeoboxes 2)
Canis lupus familiaris (dog) : ZHX2 (zinc fingers and homeoboxes 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zhx2 (zinc fingers and homeoboxes 2)
Sus scrofa (pig) : ZHX2 (zinc fingers and homeoboxes 2)
Chlorocebus sabaeus (African green monkey) : ZHX2 (zinc fingers and homeoboxes 2)
Heterocephalus glaber (naked mole-rat) : Zhx2 (zinc fingers and homeoboxes 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1557,694,665 - 57,839,832 (+)EnsemblGRCm38mm10GRCm38
GRCm381557,694,667 - 57,839,832 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371557,526,222 - 57,671,387 (+)NCBIGRCm37mm9NCBIm37
MGSCv361557,524,854 - 57,669,854 (+)NCBImm8
Celera1559,214,205 - 59,360,402 (+)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1524.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Zhx2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551442
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.