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Gene: Zhx2 (zinc fingers and homeoboxes 2) Mus musculus
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Symbol: Zhx2
Name: zinc fingers and homeoboxes 2
Description: Predicted to have DNA-binding transcription factor activity; protein dimerization activity; and transcription corepressor activity. Involved in generation of neurons; negative regulation of gene expression; and somatic stem cell population maintenance. Localizes to the nucleus. Is expressed in brain; liver; and renal vasculature. Orthologous to human ZHX2 (zinc fingers and homeoboxes 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AFP regulator 1; Afr-1; Afr1; alpha fetoprotein regulation 1, adult; alpha-fetoprotein regulator 1; mKIAA0854; Raf; regulator of AFP; zinc finger and homeodomain protein 2; zinc fingers and homeoboxes protein 2
Orthologs:
Homo sapiens (human) : ZHX2 (zinc fingers and homeoboxes 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Zhx2 (zinc fingers and homeoboxes 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zhx2 (zinc fingers and homeoboxes 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ZHX2 (zinc fingers and homeoboxes 2)
Canis lupus familiaris (dog) : ZHX2 (zinc fingers and homeoboxes 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zhx2 (zinc fingers and homeoboxes 2)
Sus scrofa (pig) : ZHX2 (zinc fingers and homeoboxes 2)
Chlorocebus sabaeus (African green monkey) : ZHX2 (zinc fingers and homeoboxes 2)
Heterocephalus glaber (naked mole-rat) : Zhx2 (zinc fingers and homeoboxes 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1557,694,665 - 57,839,832 (+)EnsemblGRCm38mm10GRCm38
GRCm381557,694,667 - 57,839,832 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371557,526,222 - 57,671,387 (+)NCBIGRCm37mm9NCBIm37
MGSCv361557,524,854 - 57,669,854 (+)NCBImm8
Celera1559,214,205 - 59,360,402 (+)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1524.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Zhx2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551442
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.