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Gene: Rab27a (RAB27A, member RAS oncogene family) Mus musculus
Symbol: Rab27a
Name: RAB27A, member RAS oncogene family
Description: Exhibits GTP binding activity; GTPase activity; and myosin V binding activity. Involved in several processes, including leukocyte degranulation; melanocyte differentiation; and melanosome transport. Localizes to the Golgi apparatus; cytoplasmic vesicle; and photoreceptor outer segment. Used to study Hermansky-Pudlak syndrome 1; hemophagocytic lymphohistiocytosis; and platelet storage pool deficiency. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Is expressed in 4-cell stage embryo; endocrine gland; lip; paravertebral ganglion; and thymus primordium. Orthologous to human RAB27A (RAB27A, member RAS oncogene family).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash; ashen; ras-related protein Rab-27A
Homo sapiens (human) : RAB27A (RAB27A, member RAS oncogene family)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rab27a (RAB27A, member RAS oncogene family)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rab27a (RAB27A, member RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAB27A (RAB27A, member RAS oncogene family)
Canis lupus familiaris (dog) : RAB27A (RAB27A, member RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rab27a (RAB27A, member RAS oncogene family)
Sus scrofa (pig) : RAB27A (RAB27A, member RAS oncogene family)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38973,044,810 - 73,097,623 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37972,892,672 - 72,945,399 (+)NCBIGRCm37mm9NCBIm37
MGSCv36972,841,997 - 72,894,724 (+)NCBImm8
Celera970,230,976 - 70,283,828 (+)NCBICelera
Cytogenetic Map9 DNCBI
cM Map940.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rab27a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551470
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.