Gene: Rab27a (RAB27A, member RAS oncogene family) Mus musculus
Analyze
Symbol:
Rab27a
Name:
RAB27A, member RAS oncogene family
Description:
Exhibits GTP binding activity; GTPase activity; and myosin V binding activity. Involved in several processes, including leukocyte degranulation; melanocyte differentiation; and melanosome transport. Localizes to the Golgi apparatus; cytoplasmic vesicle; and photoreceptor outer segment. Used to study Hermansky-Pudlak syndrome 1; hemophagocytic lymphohistiocytosis; and platelet storage pool deficiency. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Is expressed in 4-cell stage embryo; endocrine gland; lip; paravertebral ganglion; and thymus primordium. Orthologous to human RAB27A (RAB27A, member RAS oncogene family).
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash; ashen; ras-related protein Rab-27A
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
RAB27A (RAB27A, member RAS oncogene family)
HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
Rab27a (RAB27A, member RAS oncogene family)
HGNC
NCBI, HomoloGene, Inparanoid, Panther, PhylomeDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Rab27a (RAB27A, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
RAB27A (RAB27A, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
RAB27A (RAB27A, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Rab27a (RAB27A, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
RAB27A (RAB27A, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
RAB27B (RAB27B, member RAS oncogene family)
HGNC
OrthoDB
Homo sapiens (human):
RAB26 (RAB26, member RAS oncogene family)
HGNC
Panther
Homo sapiens (human):
RAB37 (RAB37, member RAS oncogene family)
HGNC
Panther
Homo sapiens (human):
RAB33B (RAB33B, member RAS oncogene family)
HGNC
Panther
Homo sapiens (human):
RAB33A (RAB33A, member RAS oncogene family)
HGNC
Panther
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Rab27a (RAB27A, member RAS oncogene family)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Homo sapiens (human):
RAB27A (RAB27A, member RAS oncogene family)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
rab27a (RAB27A, member RAS oncogene family)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, ZFIN)
Caenorhabditis elegans (roundworm):
aex-6
Alliance
DIOPT (Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup)
Drosophila melanogaster (fruit fly):
Rab27
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 9 73,044,810 - 73,097,623 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 9 72,892,672 - 72,945,399 (+) NCBI GRCm37 mm9 NCBIm37 MGSCv36 9 72,841,997 - 72,894,724 (+) NCBI mm8 Celera 9 70,230,976 - 70,283,828 (+) NCBI Celera Cytogenetic Map 9 D NCBI cM Map 9 40.08 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
Griscelli syndrome ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli disease ClinVar Griscelli syndrome ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli disease ClinVar PMID:10835631 more ... Griscelli syndrome ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli disease ClinVar PMID:28492532 Griscelli syndrome ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli disease ClinVar PMID:25741868 Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by null ClinVar PMID:12058346 , PMID:8319705 Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli syndrome type 2 ClinVar PMID:28492532 , PMID:29522846 Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli syndrome type 2 ClinVar PMID:10835631 more ... Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli syndrome type 2 ClinVar PMID:10835631 more ... Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli syndrome type 2 ClinVar PMID:23160464 , PMID:28492532 Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli syndrome type 2 ClinVar PMID:16278825 more ... Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli syndrome type 2 ClinVar PMID:25741868 , PMID:27016801 Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli syndrome type 2 ClinVar Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli syndrome type 2 ClinVar PMID:25741868 Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by term: Griscelli syndrome type 2 ClinVar PMID:28492532 Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by null ClinVar PMID:10835631 , PMID:15163896 Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by OMIM:607624 ClinVar PMID:10835631 Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by OMIM:607624 ClinVar PMID:15163896 Griscelli syndrome type 2 ISO RGD:1354398 8554872 ClinVar Annotator: match by OMIM:607624 ClinVar PMID:12531900
Imported Annotations - MGI
hemophagocytic lymphohistiocytosis IEA 13592920 MouseDO Hermansky-Pudlak syndrome 1 IEA 13592920 OMIM:203300 MouseDO platelet storage pool deficiency IEA 13592920 OMIM:185050 MouseDO
Imported Annotations - OMIM
Griscelli syndrome type 2 ISO RGD:1354398 7240710 OMIM
17beta-estradiol increases expression ISO RGD:620918 6480464 Estradiol results in increased expression of RAB27A mRNA CTD PMID:22946080 17beta-estradiol multiple interactions ISO RGD:620918 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of RAB27A mRNA CTD PMID:26496021 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:1354398 6480464 Dihydrotestosterone results in increased expression of RAB27A mRNA CTD PMID:29581250 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of RAB27A mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of RAB27A mRNA CTD PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RAB27A mRNA CTD PMID:15034205 3H-1,2-dithiole-3-thione increases expression ISO RGD:620918 6480464 1, 2-dithiol-3-thione results in increased expression of RAB27A mRNA CTD PMID:19162173 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of RAB27A mRNA CTD PMID:28973697 4-hydroxyphenyl retinamide decreases expression EXP 6480464 Fenretinide results in decreased expression of RAB27A mRNA CTD PMID:28973697 4-vinylcyclohexene dioxide affects expression EXP 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of RAB27A mRNA CTD PMID:20829426 6-propyl-2-thiouracil decreases expression ISO RGD:620918 6480464 Propylthiouracil results in decreased expression of RAB27A mRNA CTD PMID:24780913 9-cis-retinoic acid decreases expression ISO RGD:1354398 6480464 Alitretinoin results in decreased expression of RAB27A mRNA CTD PMID:16449964 9-cis-retinoic acid decreases response to substance ISO RGD:1354398 6480464 RAB27A gene mutant form results in decreased susceptibility to Alitretinoin CTD PMID:16449964 ammonium chloride affects expression ISO RGD:620918 6480464 Ammonium Chloride affects the expression of RAB27A mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO RGD:1354398 6480464 Antirheumatic Agents results in decreased expression of RAB27A mRNA CTD PMID:24449571 arsane affects methylation ISO RGD:1354398 6480464 Arsenic affects the methylation of RAB27A gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1354398 6480464 Arsenic affects the methylation of RAB27A gene CTD PMID:25304211 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of RAB27A mRNA CTD PMID:22228805 benzo[a]pyrene increases expression ISO RGD:1354398 6480464 Benzo(a)pyrene results in increased expression of RAB27A mRNA CTD PMID:26238291 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of RAB27A mRNA CTD PMID:15034205 bisphenol A multiple interactions ISO RGD:620918 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of RAB27A mRNA, [bisphenol A co-treated with Testosterone] results in decreased expression of RAB27A mRNA CTD PMID:26496021 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of RAB27A mRNA CTD PMID:30951980 butanal decreases expression ISO RGD:1354398 6480464 butyraldehyde results in decreased expression of RAB27A mRNA CTD PMID:26079696 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon results in increased expression of RAB27A mRNA CTD PMID:25554681 cisplatin increases expression ISO RGD:1354398 6480464 Cisplatin results in increased expression of RAB27A mRNA CTD PMID:27594783 cobalt dichloride decreases expression ISO RGD:1354398 6480464 cobaltous chloride results in decreased expression of RAB27A mRNA CTD PMID:19320972 , PMID:19376846 copper(II) sulfate increases expression ISO RGD:1354398 6480464 Copper Sulfate results in increased expression of RAB27A mRNA CTD PMID:19549813 crocidolite asbestos decreases expression ISO RGD:1354398 6480464 Asbestos, Crocidolite results in decreased expression of RAB27A mRNA CTD PMID:25351596 cyclosporin A increases expression ISO RGD:1354398 6480464 Cyclosporine results in increased expression of RAB27A mRNA CTD PMID:20106945 more ... dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of RAB27A mRNA CTD PMID:17361019 , PMID:21266533 diethyl maleate decreases expression ISO RGD:620918 6480464 diethyl maleate results in decreased expression of RAB27A mRNA CTD PMID:21161181 diethylstilbestrol increases expression ISO RGD:620918 6480464 Diethylstilbestrol results in increased expression of RAB27A mRNA CTD PMID:22946080 diuron increases expression ISO RGD:620918 6480464 Diuron results in increased expression of RAB27A mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:1354398 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 entinostat decreases expression ISO RGD:1354398 6480464 entinostat results in decreased expression of RAB27A mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:1354398 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB27A mRNA CTD PMID:27188386 ethyl methanesulfonate increases expression ISO RGD:1354398 6480464 Ethyl Methanesulfonate results in increased expression of RAB27A mRNA CTD PMID:23649840 gentamycin increases expression ISO RGD:620918 6480464 Gentamicins results in increased expression of RAB27A mRNA CTD PMID:22061828 irinotecan affects expression ISO RGD:620918 6480464 Irinotecan affects the expression of RAB27A mRNA CTD PMID:20097248 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of RAB27A mRNA CTD PMID:20003209 isotretinoin decreases expression ISO RGD:1354398 6480464 Isotretinoin results in decreased expression of RAB27A mRNA CTD PMID:20436886 leflunomide decreases expression ISO RGD:1354398 6480464 leflunomide results in decreased expression of RAB27A mRNA CTD PMID:28988120 lipopolysaccharide affects response to substance EXP 6480464 RAB27A affects the susceptibility to Lipopolysaccharides CTD PMID:21746860 lipopolysaccharide multiple interactions EXP 6480464 RAB27A protein affects the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:21746860 methoxychlor affects expression EXP 6480464 Methoxychlor affects the expression of RAB27A mRNA CTD PMID:20829426 methyl methanesulfonate increases expression ISO RGD:1354398 6480464 Methyl Methanesulfonate results in increased expression of RAB27A mRNA CTD PMID:23649840 methylmercury chloride decreases expression ISO RGD:1354398 6480464 methylmercuric chloride results in decreased expression of RAB27A mRNA CTD PMID:28001369 mono(2-ethylhexyl) phthalate decreases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of RAB27A mRNA CTD PMID:22401849 nickel atom increases expression ISO RGD:1354398 6480464 Nickel results in increased expression of RAB27A mRNA CTD PMID:24768652 , PMID:25583101 paracetamol decreases expression ISO RGD:1354398 6480464 Acetaminophen results in decreased expression of RAB27A mRNA CTD PMID:21420995 paracetamol increases expression ISO RGD:1354398 6480464 Acetaminophen results in increased expression of RAB27A mRNA CTD PMID:22230336 potassium chromate decreases expression ISO RGD:1354398 6480464 potassium chromate(VI) results in decreased expression of RAB27A mRNA CTD PMID:22714537 SB 431542 multiple interactions ISO RGD:1354398 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silicon dioxide decreases expression ISO RGD:1354398 6480464 Silicon Dioxide analog results in decreased expression of RAB27A mRNA, Silicon Dioxide results in decreased expression of RAB27A mRNA CTD PMID:25351596 , PMID:25895662 sodium arsenite increases expression ISO RGD:1354398 6480464 sodium arsenite results in increased expression of RAB27A mRNA CTD PMID:24431212 , PMID:28595984 sodium arsenite affects expression ISO RGD:1354398 6480464 sodium arsenite affects the expression of RAB27A mRNA CTD PMID:29319823 T-2 Toxin decreases expression ISO RGD:620918 6480464 T-2 Toxin results in decreased expression of RAB27A mRNA CTD PMID:26141394 tert-butyl hydroperoxide increases expression ISO RGD:1354398 6480464 tert-Butylhydroperoxide results in increased expression of RAB27A mRNA CTD PMID:15336504 testosterone multiple interactions ISO RGD:620918 6480464 [bisphenol A co-treated with Testosterone] results in decreased expression of RAB27A mRNA CTD PMID:26496021 testosterone enanthate affects expression ISO RGD:1354398 6480464 testosterone enanthate affects the expression of RAB27A mRNA CTD PMID:17440010 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of RAB27A mRNA CTD PMID:23557971 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of RAB27A mRNA CTD PMID:19042947 tungsten decreases expression EXP 6480464 Tungsten results in decreased expression of RAB27A mRNA CTD PMID:30912803 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of RAB27A mRNA CTD PMID:17963808 valproic acid decreases expression ISO RGD:1354398 6480464 Valproic Acid results in decreased expression of RAB27A mRNA CTD PMID:28001369 valproic acid multiple interactions ISO RGD:1354398 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB27A mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:1354398 6480464 Valproic Acid results in increased expression of RAB27A mRNA CTD PMID:23179753 more ... vinclozolin affects expression ISO RGD:620918 6480464 vinclozolin affects the expression of RAB27A mRNA CTD PMID:19015723
Biological Process
antigen processing and presentation ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 blood coagulation IMP MGI:MGI:1856656 2290270 (MGI:MGI:1860659, PMID:10859366) MGI MGI:MGI:1860659 , PMID:10859366 complement-dependent cytotoxicity ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 cytotoxic T cell degranulation IMP MGI:MGI:1856656 2290270 (MGI:MGI:3653524, PMID:11266473) MGI MGI:MGI:3653524 , PMID:11266473 exocytosis ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 exosomal secretion ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 intracellular protein transport IBA MGI:MGI:1914292 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 melanocyte differentiation IMP MGI:MGI:1856656 2290270 (MGI:MGI:77000, PMID:2379821) MGI MGI:MGI:52947 more ... melanosome localization ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 melanosome localization IMP MGI:MGI:1856656 2290270 (MGI:MGI:1930900, PMID:11266470) MGI MGI:MGI:1930900 , PMID:11266470 melanosome transport IMP MGI:MGI:1856656 2290270 (MGI:MGI:3653524, PMID:11266473) MGI MGI:MGI:3653524 , PMID:11266473 melanosome transport IBA MGI:MGI:1861441 , PANTHER:PTN001178482 2290270 (PMID:21873635) GO_Central PMID:21873635 multivesicular body organization ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 multivesicular body sorting pathway ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 natural killer cell degranulation IMP MGI:MGI:1856656 2290270 (MGI:MGI:3653524, PMID:11266473) MGI MGI:MGI:3653524 , PMID:11266473 pigment granule localization IMP MGI:MGI:1856656 2290270 (MGI:MGI:3047015 more ... MGI MGI:MGI:3047015 more ... pigment granule transport IMP MGI:MGI:1856656 2290270 (MGI:MGI:3512820, PMID:15572405) MGI MGI:MGI:3512820 , PMID:15572405 pigmentation IMP MGI:MGI:1856656 2290270 (MGI:MGI:77000, PMID:2379821) MGI MGI:MGI:77000 , PMID:2379821 positive regulation of constitutive secretory pathway ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of exocytosis ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of exocytosis IBA PANTHER:PTN001178482 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 positive regulation of gene expression ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of phagocytosis ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of reactive oxygen species biosynthetic process ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of regulated secretory pathway ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 protein targeting IMP MGI:MGI:1856656 2290270 (MGI:MGI:1930900 more ... MGI MGI:MGI:1930900 more ... Rab protein signal transduction IBA FB:FBgn0015790 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 vesicle-mediated transport IMP MGI:MGI:1856656 2290270 (MGI:MGI:1860659, PMID:10859366) MGI MGI:MGI:1860659 , PMID:10859366
Cellular Component
apical plasma membrane ISO RGD:620918 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 dendrite ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 endosome IEA UniProtKB-KW:KW-0967 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 exocytic vesicle ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 Golgi apparatus IDA 2290270 (MGI:MGI:3040020, PMID:14724135) MGI MGI:MGI:3040020 , PMID:14724135 intracellular ISS 2290270 (MGI:MGI:1860659, PMID:10859366) MGI MGI:MGI:1860659 , PMID:10859366 late endosome ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 lysosome ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 melanosome ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 melanosome IBA MGI:MGI:1861441 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 melanosome IDA 2290270 (MGI:MGI:2180422 more ... UniProtKB MGI:MGI:2180422 more ... membrane IEA UniProtKB-KW:KW-0472 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 multivesicular body membrane ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 photoreceptor outer segment IDA 2290270 (MGI:MGI:2180422, PMID:11964381) UniProtKB MGI:MGI:2180422 , PMID:11964381 secretory granule IMP MGI:MGI:1856656 2290270 (MGI:MGI:3653524, PMID:11266473) MGI MGI:MGI:3653524 , PMID:11266473 secretory granule IBA MGI:MGI:1861441 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 secretory granule ISO RGD:620918 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 secretory granule membrane ISO RGD:620918 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 Weibel-Palade body ISO RGD:620918 2290270 RGD GO_REF:0000096, MGI:MGI:4417868
Molecular Function
GDP binding ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 GTP binding ISO UniProtKB:P51159 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 GTP binding IDA 2290270 (MGI:MGI:4412435, PMID:18940603) UniProtKB MGI:MGI:4412435 , PMID:18940603 GTPase activity IDA 2290270 (MGI:MGI:4412435, PMID:18940603) UniProtKB MGI:MGI:4412435 , PMID:18940603 GTPase activity IBA FB:FBgn0015790 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 GTPase activity IBA FB:FBgn0015790 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 myosin V binding IPI UniProtKB:Q99104 2290270 (MGI:MGI:1930900, PMID:11266470) MGI MGI:MGI:1930900 , PMID:11266470 nucleotide binding IEA UniProtKB-KW:KW-0547 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 protein binding IPI UniProtKB:Q768S4 2290270 (MGI:MGI:2656989, PMID:12578829) MGI MGI:MGI:2656989 , PMID:12578829 protein binding IPI UniProtKB:Q0VAV2 2290270 (MGI:MGI:2176311, PMID:11773082) UniProtKB MGI:MGI:2176311 , PMID:11773082 protein binding IPI UniProtKB:Q9HCH5 2290270 (MGI:MGI:4412435, PMID:18940603) UniProtKB MGI:MGI:4412435 , PMID:18940603 protein binding IPI UniProtKB:Q99N50 , UniProtKB:Q99N80 2290270 (MGI:MGI:3852304, PMID:18266782) UniProtKB MGI:MGI:3852304 , PMID:18266782 protein binding IPI UniProtKB:P47708 more ... 2290270 (MGI:MGI:2176311, PMID:11773082) UniProtKB MGI:MGI:2176311 , PMID:11773082 protein binding IPI UniProtKB:Q9IV27 2290270 (MGI:MGI:2176311, PMID:11773082) UniProtKB MGI:MGI:2176311 , PMID:11773082 protein binding IPI UniProtKB:B2RUP2 2290270 (MGI:MGI:3778349, PMID:18354201) UniProtKB MGI:MGI:3778349 , PMID:18354201 protein binding IPI UniProtKB:Q8NFW9 2290270 (MGI:MGI:2180422, PMID:11964381) UniProtKB MGI:MGI:2180422 , PMID:11964381 protein binding IPI UniProtKB:Q8TDW5 2290270 (MGI:MGI:4942255, PMID:12051743) IntAct MGI:MGI:4942255 , PMID:12051743 protein binding IPI UniProtKB:P47708 2290270 (MGI:MGI:4839453, PMID:14722103) IntAct MGI:MGI:4839453 , PMID:14722103 protein binding IPI UniProtKB:Q91V27 2290270 (MGI:MGI:2176311 more ... UniProtKB MGI:MGI:2176311 more ... protein binding IPI UniProtKB:P47708 , UniProtKB:Q91V27 2290270 (MGI:MGI:2176311, PMID:11773082) IntAct MGI:MGI:2176311 , PMID:11773082 protein binding IPI UniProtKB:Q9HCH5 , UniProtKB:Q9R0Q1-1 2290270 (MGI:MGI:4412435, PMID:18940603) IntAct MGI:MGI:4412435 , PMID:18940603 protein binding IPI UniProtKB:Q8K3I4 2290270 (MGI:MGI:2657090, PMID:12590134) MGI MGI:MGI:2657090 , PMID:12590134 protein binding IPI UniProtKB:Q99N80 2290270 (MGI:MGI:2657090, PMID:12590134) MGI MGI:MGI:2657090 , PMID:12590134 protein binding IPI UniProtKB:Q99N48 2290270 (MGI:MGI:2657090, PMID:12590134) MGI MGI:MGI:2657090 , PMID:12590134 protein binding IPI UniProtKB:Q9R0Q1 2290270 (MGI:MGI:2657090, PMID:12590134) MGI MGI:MGI:2657090 , PMID:12590134 protein binding IPI UniProtKB:Q99104 2290270 (MGI:MGI:3028456, PMID:14730011) MGI MGI:MGI:3028456 , PMID:14730011 protein binding IPI UniProtKB:Q80T23 2290270 (MGI:MGI:2657090, PMID:12590134) MGI MGI:MGI:2657090 , PMID:12590134 protein domain specific binding ISO RGD:620918 2290270 RGD GO_REF:0000096, MGI:MGI:4417868