Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Rab27a (RAB27A, member RAS oncogene family) Mus musculus
Analyze
Symbol: Rab27a
Name: RAB27A, member RAS oncogene family
Description: Exhibits GTP binding activity; GTPase activity; and myosin V binding activity. Involved in several processes, including leukocyte degranulation; melanocyte differentiation; and melanosome transport. Localizes to the Golgi apparatus; cytoplasmic vesicle; and photoreceptor outer segment. Used to study Hermansky-Pudlak syndrome 1; hemophagocytic lymphohistiocytosis; and platelet storage pool deficiency. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Is expressed in 4-cell stage embryo; endocrine gland; lip; paravertebral ganglion; and thymus primordium. Orthologous to human RAB27A (RAB27A, member RAS oncogene family).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash; ashen; ras-related protein Rab-27A
Orthologs:
Homo sapiens (human) : RAB27A (RAB27A, member RAS oncogene family)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rab27a (RAB27A, member RAS oncogene family)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rab27a (RAB27A, member RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAB27A (RAB27A, member RAS oncogene family)
Canis lupus familiaris (dog) : RAB27A (RAB27A, member RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rab27a (RAB27A, member RAS oncogene family)
Sus scrofa (pig) : RAB27A (RAB27A, member RAS oncogene family)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38973,044,810 - 73,097,623 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37972,892,672 - 72,945,399 (+)NCBIGRCm37mm9NCBIm37
MGSCv36972,841,997 - 72,894,724 (+)NCBImm8
Celera970,230,976 - 70,283,828 (+)NCBICelera
Cytogenetic Map9 DNCBI
cM Map940.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rab27a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551470
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.